ID Q5JF90_THEKO Unreviewed; 747 AA.
AC Q5JF90;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:BAD84827.1};
GN OrderedLocusNames=TK0638 {ECO:0000313|EMBL:BAD84827.1};
OS Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS (Pyrococcus kodakaraensis (strain KOD1)).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=69014 {ECO:0000313|EMBL:BAD84827.1, ECO:0000313|Proteomes:UP000000536};
RN [1] {ECO:0000313|EMBL:BAD84827.1, ECO:0000313|Proteomes:UP000000536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-918 / JCM 12380 / KOD1
RC {ECO:0000313|Proteomes:UP000000536};
RX PubMed=15710748; DOI=10.1101/gr.3003105;
RA Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL Genome Res. 15:352-363(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; AP006878; BAD84827.1; -; Genomic_DNA.
DR RefSeq; WP_011249589.1; NC_006624.1.
DR AlphaFoldDB; Q5JF90; -.
DR STRING; 69014.TK0638; -.
DR EnsemblBacteria; BAD84827; BAD84827; TK0638.
DR GeneID; 78447152; -.
DR KEGG; tko:TK0638; -.
DR PATRIC; fig|69014.16.peg.619; -.
DR eggNOG; arCOG02320; Archaea.
DR eggNOG; arCOG02362; Archaea.
DR HOGENOM; CLU_000445_107_19_2; -.
DR InParanoid; Q5JF90; -.
DR OrthoDB; 342253at2157; -.
DR PhylomeDB; Q5JF90; -.
DR Proteomes; UP000000536; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000536};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 390..442
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 461..718
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT COILED 458..489
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 676..744
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 747 AA; 82189 MW; CB96B9E38FD86193 CRC64;
MEFKKKIISI VVLGFVIVAV LTSGMLLYSE NNMANEIETQ LTPLMQQWAE QTVSAKSEAL
AKEFQAFFDE VEALGTTTEK LAVIGIQELE SEGYKFGEGD YVEPLNEILM EHFETVAAAD
SRISSVYFGD KYGNMFIYPE QELPEGYDPR VRPWYQEAVK AGKGVWSDPY QDASSGKWVV
TYAVPIYRNG ELIGVIGLDV FIDTLVNEIK SVKVGETGYA YVVNEDGLII AHPNEQYVMK
LNVFEQESLK PIADIVRSGK DSGVVTYEWQ GVKATAAGYK IPSTGWYVFT KVPTAEVTEG
VMAVIRTVQD NTQKTTYMMI VLLLAISTVI VLAAYRLIST SLMPLVALGA AAQALAEGKL
SEVKEKLRGI QYLEEDEIGM LIKAFESVSK DMVGTLQGIA EKLERLAEGD LSNGLSVEAK
GELREIIEDV KDMSTKMREL LGNIVGLTEK LEKHANMLAQ VANDVTEAIN QVNEAVQQVS
IEAQRQQENI NEITEGMRLV ADMSEESVRA MEEFEGAVNE VVHIADEGRQ KGEVSAQQIQ
SIQEMMGNIE AAVNRVNEMS RSIEEITNVI TGIAEQTNLL ALNAAIEAAR AGEAGRGFAV
VAQEIRNLAE ESKKAADNIK EIIGRMTDEI KDAVNATQRG VSVVSESSET LRETTEYLTN
IAELISDTGA RLGHVKEQIL RTQEEVDKAL KALENLAASA EETTASAEEV SSAVEEQTAA
IEELKRAADE LKKIVDELRR QTSNFRL
//
