ID Q5KBG2_CRYNJ Unreviewed; 448 AA.
AC Q5KBG2;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=PWWP domain-containing protein {ECO:0000259|PROSITE:PS50812};
GN OrderedLocusNames=CNI02650 {ECO:0000313|EMBL:AAW45692.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW45692.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW45692.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017349; AAW45692.1; -; Genomic_DNA.
DR RefSeq; XP_572999.1; XM_572999.1.
DR AlphaFoldDB; Q5KBG2; -.
DR STRING; 214684.Q5KBG2; -.
DR PaxDb; 214684-Q5KBG2; -.
DR EnsemblFungi; AAW45692; AAW45692; CNI02650.
DR GeneID; 3259576; -.
DR KEGG; cne:CNI02650; -.
DR VEuPathDB; FungiDB:CNI02650; -.
DR eggNOG; ENOG502RZNI; Eukaryota.
DR HOGENOM; CLU_043161_0_0_1; -.
DR InParanoid; Q5KBG2; -.
DR OMA; WPVIVCD; -.
DR OrthoDB; 4271850at2759; -.
DR Proteomes; UP000002149; Chromosome 9.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR CDD; cd05840; PWWP_ScIOC4-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035503; IOC4-like_PWWP.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR PANTHER; PTHR12550; HEPATOMA-DERIVED GROWTH FACTOR-RELATED; 1.
DR PANTHER; PTHR12550:SF49; JIL-1 ANCHORING AND STABILIZING PROTEIN, ISOFORM A; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002149}.
FT DOMAIN 36..100
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..417
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 49356 MW; 720DAC3818929921 CRC64;
MSSSPARDDK PAPAKKPAPR PRAAAAKPPA DHKFDIGDIV LARLRGYPPW PARIANPETL
PRNVLKTRPG KNPNLYCCQF FPAGDFSWLQ NKDIKALSAS DISSFLAQPH RKSSGGLREA
YQTAQDPTEW DAQQEEIHKQ QEEAEANVDE LEDEDEAEVV VKAGKRKREE PKRKKAAKKE
EEPKPKKAKA VSKAVSKAGD KKAVSKTEVD EDPLASDPEC VKVKDWRHKL QKAFLGESMP
AEPEMSHWNE VFESIESYDS MTIEALQYSK IGKVMKKIMG LTTIPLNDKY DFTRRAGKLM
HQWQEFIDAA NRGRVTNGQK KSARPPSAPS AAATAAEEET PAKEDKPADE TPAEEKKEES
AEPVAEKKEE SAEPVTEKKE ESAELVTEGK MELDEKEKEA AAEEPAAAEK TEEVGAGAGE
EAEAAEAPEP EAAEKPEANG EDKMQVDA
//
