ID Q5KJS7_CRYNJ Unreviewed; 239 AA.
AC Q5KJS7;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 2.
DT 24-JAN-2024, entry version 85.
DE RecName: Full=PARP-type domain-containing protein {ECO:0000259|PROSITE:PS50064};
GN OrderedLocusNames=CNC05510 {ECO:0000313|EMBL:AAW42446.2};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW42446.2, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW42446.2, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017343; AAW42446.2; -; Genomic_DNA.
DR RefSeq; XP_569753.1; XM_569753.1.
DR AlphaFoldDB; Q5KJS7; -.
DR STRING; 214684.Q5KJS7; -.
DR PaxDb; 214684-Q5KJS7; -.
DR EnsemblFungi; AAW42446; AAW42446; CNC05510.
DR VEuPathDB; FungiDB:CNC05510; -.
DR HOGENOM; CLU_045993_3_0_1; -.
DR InParanoid; Q5KJS7; -.
DR OrthoDB; 2787561at2759; -.
DR Proteomes; UP000002149; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.1740.10; Zinc finger, PARP-type; 1.
DR InterPro; IPR001510; Znf_PARP.
DR InterPro; IPR036957; Znf_PARP_sf.
DR Pfam; PF00645; zf-PARP; 1.
DR SMART; SM01336; zf-PARP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS50064; ZF_PARP_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 4..89
FT /note="PARP-type"
FT /evidence="ECO:0000259|PROSITE:PS50064"
FT REGION 86..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 239 AA; 27006 MW; BCDF182F39971912 CRC64;
MPAYRVELAH TGRAGCNGRK PCNGTKIGKG ELRLGVWVEI RGNGGFKWRH WGCTTPEVIK
HWKEDFEKPS EIDGFEEIPE EYQQKVTDAW NEGHVKEEDV PETARVEKVE ENEPEDEKPA
TKKKGTKKAK AEANEDEGSP EAPKKQKAPA KESKAKNEPK HEDENEVEAS PKKKRKAPVK
QAKKKEPEEH EEPAAEEGPK KKRKAAVKEA EKAEPSDNVE EKPEEKPKRG RGRPKKTEA
//
