ID Q5KN33_CRYNJ Unreviewed; 1184 AA.
AC Q5KN33; Q55YR2;
DT 15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2005, sequence version 1.
DT 24-JAN-2024, entry version 109.
DE RecName: Full=SCD domain-containing protein {ECO:0000259|PROSITE:PS51425};
GN OrderedLocusNames=CNA07890 {ECO:0000313|EMBL:AAW41317.1};
OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS MYA-565) (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=214684 {ECO:0000313|EMBL:AAW41317.1, ECO:0000313|Proteomes:UP000002149};
RN [1] {ECO:0000313|EMBL:AAW41317.1, ECO:0000313|Proteomes:UP000002149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEC21 / ATCC MYA-565 {ECO:0000313|Proteomes:UP000002149};
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
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DR EMBL; AE017341; AAW41317.1; -; Genomic_DNA.
DR RefSeq; XP_567136.1; XM_567136.1.
DR AlphaFoldDB; Q5KN33; -.
DR STRING; 214684.Q5KN33; -.
DR PaxDb; 214684-Q5KN33; -.
DR EnsemblFungi; AAW41317; AAW41317; CNA07890.
DR GeneID; 3253205; -.
DR KEGG; cne:CNA07890; -.
DR VEuPathDB; FungiDB:CNA07890; -.
DR eggNOG; KOG2011; Eukaryota.
DR HOGENOM; CLU_003349_0_0_1; -.
DR InParanoid; Q5KN33; -.
DR OMA; YDHSQIP; -.
DR OrthoDB; 5354237at2759; -.
DR Proteomes; UP000002149; Chromosome 1.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0008278; C:cohesin complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0007062; P:sister chromatid cohesion; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039662; Cohesin_Scc3/SA.
DR InterPro; IPR020839; SCD.
DR InterPro; IPR013721; STAG.
DR PANTHER; PTHR11199:SF0; LD34181P-RELATED; 1.
DR PANTHER; PTHR11199; STROMAL ANTIGEN; 1.
DR Pfam; PF21581; SCD; 1.
DR Pfam; PF08514; STAG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51425; SCD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002149}.
FT DOMAIN 333..418
FT /note="SCD"
FT /evidence="ECO:0000259|PROSITE:PS51425"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 297..331
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 27..42
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1184 AA; 133373 MW; 7AD999BB0DDB9A19 CRC64;
MSSPEPEEPR RGARVRKQVN KFDASQQNGR GKRKHIEDRE DDDQEGLIPD PEDESDHEPT
PKKKKPAAPR KSRASAGTTK KDGPKTKTKP AAEGVSEIVE KTDSPLFNAL QQPDIALQPL
IDEWIETYQQ AAGDEISEQK SIHELVVFFI RCCGMTTEIE QAEATDDDGI PDVIERVQDE
SVRVALATYP LISKAKNFKP FKSNLNEFIS HFISSLALTP ILFHTADNTP HSSLLIPLLL
NWLMCMSSST LRPIRHTSTY VTLRMNSALC DVAADVSKDL SVKQRQRDAE VRKAGATNAA
QKRVKAAEDR VKEVQERKQT LEELMQEIFD VMFVHRVRDA DPNIRTDCLR ELGLWAKKHP
EYYVSTSYLS YFTRGCNDTH AHARLETVKA LANLYIRETF ISNARTLTMR LAPRVIEMAT
RDVDLNVRVV ALQVITLIDK TGILQDEEDE ERDKVAKLVF DQEPRIRKAA GAFILGLWEE
RKEGLKAVWS GLRANKKKRA ANITEDEMSN YLNWKSLAAV LLYTSKSLDD DPSGQPSALK
PSLLIPSLPN TQMTRATAAV ESIGAEHELW KDWESLVDYL LVDHSTNEED MWLLREDEET
FMLQVLLACI KREENEEDEP DRTKTLIKVL PRLFAKHQAD VGRMTGILSV PGHMKLSLYL
DMRMSSAYES LWDDISKQFL KYTSPTILTA SISAISHLVG NSSLSSINET KLSELHESLF
ASLRDAIGSE DVALVTLEDE QISQLEAIML RITLLQRSMD LVDVMEDEEG QQSSGWDIIC
AFADRGKLGY KEEATMVDYA VQIIFLHITW LFKRFTKEDA QDATKIDLLS TRRDTALQTF
NQLFLGETTN TASAVRRQAF ISFINTYVLF AKRAEGRGGA PASDVCSVTM PEEVQHRLGG
AFQAVIERYA SVVETRSAGR EESQQPPELT PDEMHEDFQF FQLVSVFVGA IRCGVLEVEH
AKEPLAHYSR FGPTYDAIVK KLVDVLRDEG IYNREADAVQ HVAGSALQQS FNIFLDSEED
EPTAPLALAR VIATAFVIHG SQFAILRQLH PSDVCDFHLE ALDFVSLKVS TIVKQEGNAR
NKEQKSRLTR KKWAVLTFFK VLVPLLAPVT GRDALKIKAH LEDVIDSSGV QLTTNKGWDG
YRAYEKRLVG IASKDPNVKM MASKKVVERE DTEQGDEDNV FARQ
//
