ID Q5KW42_GEOKA Unreviewed; 389 AA.
AC Q5KW42;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Acetoin utilization protein AcuC {ECO:0000256|ARBA:ARBA00020218};
GN OrderedLocusNames=GK2809 {ECO:0000313|EMBL:BAD77094.1};
OS Geobacillus kaustophilus (strain HTA426).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC Geobacillus thermoleovorans group.
OX NCBI_TaxID=235909 {ECO:0000313|EMBL:BAD77094.1, ECO:0000313|Proteomes:UP000001172};
RN [1] {ECO:0000313|EMBL:BAD77094.1, ECO:0000313|Proteomes:UP000001172}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTA426 {ECO:0000313|EMBL:BAD77094.1,
RC ECO:0000313|Proteomes:UP000001172};
RX PubMed=15576355; DOI=10.1093/nar/gkh970;
RA Takami H., Takaki Y., Chee G.J., Nishi S., Shimamura S., Suzuki H.,
RA Matsui S., Uchiyama I.;
RT "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT Geobacillus kaustophilus.";
RL Nucleic Acids Res. 32:6292-6303(2004).
CC -!- PATHWAY: Ketone degradation; acetoin degradation.
CC {ECO:0000256|ARBA:ARBA00005101}.
CC -!- SIMILARITY: Belongs to the histone deacetylase family.
CC {ECO:0000256|ARBA:ARBA00005947}.
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DR EMBL; BA000043; BAD77094.1; -; Genomic_DNA.
DR RefSeq; WP_011232283.1; NC_006510.1.
DR AlphaFoldDB; Q5KW42; -.
DR STRING; 235909.GK2809; -.
DR KEGG; gka:GK2809; -.
DR eggNOG; COG0123; Bacteria.
DR HOGENOM; CLU_007727_8_0_9; -.
DR UniPathway; UPA00040; -.
DR Proteomes; UP000001172; Chromosome.
DR GO; GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd09994; HDAC_AcuC_like; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR003085; AcuC.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF13; HISTONE DEACETYLASE HDAC1; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01272; ACUCPROTEIN.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 3: Inferred from homology;
KW Acetoin catabolism {ECO:0000256|ARBA:ARBA00022627};
KW Reference proteome {ECO:0000313|Proteomes:UP000001172}.
FT DOMAIN 22..317
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 389 AA; 43430 MW; 5735194E4557D007 CRC64;
MSRNCAFVYS EQFLQYKFHD DHPFNQLRVK MTYDLLCTLG ALEDRQIVAP RMATDDELAL
IHDRSYIEAV KAAGRGELSE AAAQNYGLGT EDTPIFPNMH EASALLVGST LTAVDAVLSG
AAEHALNLGG GLHHGFRGKA SGFCVYNDSA VAIQYIREKY GLRVLYVDTD AHHGDGVQWA
FYDDPNVCTF SIHETGRYLF PGTGNVNERG LGAGYGYSFN IPVDAFTEDE SWIAAYTTAL
REIADFFRPD VIVTQNGVDA HYYDPLTHLS VTMKTYRAIP KLAHEIAHEY CGGRWIAVGG
GGYDIWRVVP RAWALLWLEM TGQADVSGPL PDEWRERWQP LSPVALPLEW DDPDDLYPPI
PRKAEISEKN AQTVEKALYF IRSQRRAGT
//
