ID Q5KZU6_GEOKA Unreviewed; 560 AA.
AC Q5KZU6;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Long-chain fatty-acid-CoA ligase {ECO:0000313|EMBL:BAD75790.1};
GN OrderedLocusNames=GK1505 {ECO:0000313|EMBL:BAD75790.1};
OS Geobacillus kaustophilus (strain HTA426).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC Geobacillus thermoleovorans group.
OX NCBI_TaxID=235909 {ECO:0000313|EMBL:BAD75790.1, ECO:0000313|Proteomes:UP000001172};
RN [1] {ECO:0000313|EMBL:BAD75790.1, ECO:0000313|Proteomes:UP000001172}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTA426 {ECO:0000313|EMBL:BAD75790.1,
RC ECO:0000313|Proteomes:UP000001172};
RX PubMed=15576355; DOI=10.1093/nar/gkh970;
RA Takami H., Takaki Y., Chee G.J., Nishi S., Shimamura S., Suzuki H.,
RA Matsui S., Uchiyama I.;
RT "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT Geobacillus kaustophilus.";
RL Nucleic Acids Res. 32:6292-6303(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BA000043; BAD75790.1; -; Genomic_DNA.
DR RefSeq; WP_011231001.1; NC_006510.1.
DR AlphaFoldDB; Q5KZU6; -.
DR STRING; 235909.GK1505; -.
DR KEGG; gka:GK1505; -.
DR PATRIC; fig|235909.7.peg.1619; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_7_9; -.
DR Proteomes; UP000001172; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:BAD75790.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001172}.
FT DOMAIN 28..409
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 463..540
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 560 AA; 62573 MW; A1DE4109EBB796BC CRC64;
MNTRHYPYWP KRLSKTLAVP ETTLVDHLET TAKRYPNKTA IYYYGAVYSY KQLLDEVNAL
AGYLQQKLSV KPGDRVLLYM QNSPQFVISY YAILRAEAIV VPINPMNTSE ELSFYVNDCE
TRVAIVGQEL LDKAAPLLGR TALEQIIVAA YSDYASDESP VSLPAEVAAP RRAIGDERIL
LWADCLGAQL PPLPYNGHVD DIAVLPYTSG TTGVPKGCIH PHRTVNANIV GAYHWGDVTS
DSVALATLPF FHVTGMVHSM HTPIFAGAAM VLMTRWDRDA AARLIELHRC THWVNISTML
IDFLANPALG RYDISSLSSI SGGGAALPEA VGEKLFQLTG VRYFEGYGLT ETISQTHFNP
PDRPKLQCLG VPSFDVDARI IDPATGRELG VGEVGEIIVC GPQVFRGYYR REKETEEAFI
ELDGKRFFRT GDIGRMDEEG YFFIVDRVKR MINASGYKVW PTEVESLLYK HPAVQQACVV
GVPDPRRGET VKAFIVLHDE YVGKVTEEEI IEWSKTQMAA YKYPRLVEFR SSLPMTSSGK
LLWRKLQEEE YEKAGKGVNN
//
