ID Q5LW00_RUEPO Unreviewed; 811 AA.
AC Q5LW00;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Aminomethyl transferase family protein {ECO:0000313|EMBL:AAV93860.1};
GN OrderedLocusNames=SPO0544 {ECO:0000313|EMBL:AAV93860.1};
OS Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter
OS pomeroyi).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=246200 {ECO:0000313|EMBL:AAV93860.1, ECO:0000313|Proteomes:UP000001023};
RN [1] {ECO:0000313|EMBL:AAV93860.1, ECO:0000313|Proteomes:UP000001023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC {ECO:0000313|Proteomes:UP000001023};
RX PubMed=15602564; DOI=10.1038/nature03170;
RA Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.,
RA Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E., Sheldon W.M.,
RA Ye W., Miller T.R., Carlton J., Rasko D.A., Paulsen I.T., Ren Q.,
RA Daugherty S.C., Deboy R.T., Dodson R.J., Durkin A.S., Madupu R.,
RA Nelson W.C., Sullivan S.A., Rosovitz M.J., Haft D.H., Selengut J., Ward N.;
RT "Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine
RT environment.";
RL Nature 432:910-913(2004).
RN [2] {ECO:0000313|EMBL:AAV93860.1, ECO:0000313|Proteomes:UP000001023}
RP GENOME REANNOTATION.
RC STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC {ECO:0000313|Proteomes:UP000001023};
RX PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA Rivers A.R., Smith C.B., Moran M.A.;
RT "An updated genome annotation for the model marine bacterium Ruegeria
RT pomeroyi DSS-3.";
RL Stand. Genomic Sci. 9:11-11(2014).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CP000031; AAV93860.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5LW00; -.
DR STRING; 246200.SPO0544; -.
DR PaxDb; 246200-SPO0544; -.
DR KEGG; sil:SPO0544; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_007884_11_0_5; -.
DR Proteomes; UP000001023; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001023};
KW Transferase {ECO:0000313|EMBL:AAV93860.1}.
FT DOMAIN 5..367
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 370..424
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 427..698
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 723..798
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 811 AA; 88758 MW; 76D5A894B2A60CDF CRC64;
MKQVRVAVIG GGVVGVSVLY HLARLGWTDC CLLERTQLTA GSTWHAAGLL PLYYPNQTMS
LINKHSMQLY ARLQAETGQP SGFHQCGQLR LATDHDRLDE YRAYLSFARY LGIDCALITR
EEAQKLWPLA DLGDVIAALY HPGDGHIAPA DLTQAMATGA RGMGAKIHLN TEATAISRTA
SGEWLISTPN GDFLAEHVVT ATGNYARQTG AMVGLNVPSI PVMHQYVVTE TIKEFADHNR
AGRPEMPVLR DDKSRFYLRQ ENDGLILGPY EPNPKSWAIN GVPPGFGAEL MTPDYDSLEP
FIEGTLRRVS SFAAAGIRTV VNGPIAHTPD AFPLVGPAPG LQNYWLAEGM VAGICYGGGV
GRYLAEWITE GAPTIDMWPV DPRRFNGHAG KNHTRLKNEE TYGHIFDIHY PNLEMPAARP
GKTSPCYDRL TRAGAVWGVA GGWERARWFD AEGNRTPETL TFRRSNAFEA IGAECRAIRN
AVGLIDFTSF AKWEVSGAGA MAFLDRALAN AMPKRDGRVT LAHALDENGR FCAEFTVARL
AEDRFYICGP AFSEVHDDHV LRSRLRPADA ATLTNVSMGW GCFTVAGPKS RELLSRIVDA
PLENDSFKWF DLHEGEVGWA TDVRLMRVNY CGELGWELHH PIAFQHHILD QLEQAGADLG
LRHVGMRALD SLRIEKSYRA VAQELTTQNT LHELGLGRFI ATGKTGFIGA QAVAERVGKE
SVKLVTLEVD CEAGGVEPAM NQAVRCGDKV IALTTSGAYG HFLGKHLAMA ILPLDHAAEG
TRLSVEILDE RYDAVVIADS PHDPGNLRPR A
//
