ID Q5MXI7_MACMU Unreviewed; 143 AA.
AC Q5MXI7;
DT 01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT 01-FEB-2005, sequence version 1.
DT 22-FEB-2023, entry version 65.
DE SubName: Full=Toll-like receptor 6 {ECO:0000313|EMBL:AAS17872.1};
DE Flags: Fragment;
GN Name=TLR6 {ECO:0000313|EMBL:AAS17872.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AAS17872.1};
RN [1] {ECO:0000313|EMBL:AAS17872.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15578265; DOI=10.1007/s00251-004-0734-6;
RA Sanghavi S.K., Shankarappa R., Reinhart T.A.;
RT "Genetic analysis of Toll/Interleukin-1 Receptor (TIR) domain sequences
RT from rhesus macaque Toll-like receptors (TLRs) 1-10 reveals high homology
RT to human TLR/TIR sequences.";
RL Immunogenetics 56:667-674(2004).
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DR EMBL; AY525616; AAS17872.1; -; mRNA.
DR AlphaFoldDB; Q5MXI7; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR017241; Toll-like_receptor.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR PANTHER; PTHR24365:SF422; TOLL-LIKE RECEPTOR 6; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 2: Evidence at transcript level;
KW Receptor {ECO:0000313|EMBL:AAS17872.1}.
FT DOMAIN 1..141
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAS17872.1"
FT NON_TER 143
FT /evidence="ECO:0000313|EMBL:AAS17872.1"
SQ SEQUENCE 143 AA; 16956 MW; DDB9EF067B2D82B8 CRC64;
QFHAFISYSE HDSAWVKNEL VPYLEKEGMQ ICLHERNFVP GKSIGENIIN CIEKSYKSIF
VLSPNFVQSE WCHYELYFAH HNLFHEGSNN LILILLEPIP QNSIPNKYHK LRALMTQRTY
LQWPKEKSKR GLFWANIRAA FNM
//
