ID Q5QE47_9NEOP Unreviewed; 390 AA.
AC Q5QE47;
DT 04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT 04-JAN-2005, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE RecName: Full=Elongation factor 1-alpha {ECO:0000256|ARBA:ARBA00013870, ECO:0000256|RuleBase:RU000325};
DE Flags: Fragment;
GN Name=EF1a {ECO:0000313|EMBL:AAV74586.1};
OS Iolana iolas (Iolas blue).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Lycaenidae; Polyommatinae; Iolana.
OX NCBI_TaxID=301168 {ECO:0000313|EMBL:AAV74586.1};
RN [1] {ECO:0000313|EMBL:AAV74586.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15549104; DOI=10.1038/nature03020;
RA Als T.D., Vila R., Kandul N.P., Nash D.R., Yen S.H., Hsu Y.F.,
RA Mignault A.A., Boomsma J.J., Pierce N.E.;
RT "The evolution of alternative parasitic life histories in large blue
RT butterflies.";
RL Nature 432:386-390(2004).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982, ECO:0000256|RuleBase:RU000325}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249,
CC ECO:0000256|RuleBase:RU000325}.
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DR EMBL; AY675367; AAV74586.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5QE47; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:AAV74586.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000325};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000325};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:AAV74586.1}.
FT DOMAIN 1..205
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAV74586.1"
FT NON_TER 390
FT /evidence="ECO:0000313|EMBL:AAV74586.1"
SQ SEQUENCE 390 AA; 42694 MW; 992388E420247DB0 CRC64;
TIEKFEKEAQ EMGKGSFKYA WVLDKLKAER ERGITIDIAL WKFETSKYYV TIIDAPGHRD
FIKNMITGTS QADCAVLIVA AGTGEFEAGI SKNGQTREHA LLAFTLGVKQ LIVGVNKMDS
TEPPYSESRF EEIKKEVSSY IKKIGYNPAA VAFVPISGWH GDNMLEVSTK MPWFKGWQVE
RKEGKAEGKC LIEALDAILP PARPTDKALR LPLQDVYKIG GIGTVPVGRV ETGVLKPGTI
VVFAPANITT EVKSVEMHHE ALQEAVPGDN VGFNVKNVSV KELRRGYVAG DSKNNPPKGA
ADFTAQVIVL NHPGQISNGY TPVLDCHTAH IACKFAEIKE KVDRRSGKST EDNPKSIKSG
DAAIVNLVPS KPLCVESFQE FPPLGRFAVR
//
