ID Q5TLD2_BOMMO Unreviewed; 259 AA.
AC Q5TLD2;
DT 21-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 21-DEC-2004, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Replication factor A protein 2 {ECO:0000256|ARBA:ARBA00043137};
GN Name=BmRPA2 {ECO:0000313|EMBL:BAD69790.1};
GN Synonyms=692485 {ECO:0000313|EnsemblMetazoa:NP_001036939.1};
OS Bombyx mori (Silk moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC Bombycidae; Bombycinae; Bombyx.
OX NCBI_TaxID=7091 {ECO:0000313|EMBL:BAD69790.1};
RN [1] {ECO:0000313|EMBL:BAD69790.1}
RP NUCLEOTIDE SEQUENCE.
RA Maeda T., Kusakabe T., Koga K., Kawaguchi Y.;
RT "Cloning and characterization of a replication protein A from silkworm,
RT Bombyx mori.";
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000005204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=p50T {ECO:0000313|Proteomes:UP000005204};
RX PubMed=19121390; DOI=10.1016/j.ibmb.2008.11.004;
RG International Silkworm Genome Consortium;
RT "The genome of a lepidopteran model insect, the silkworm Bombyx mori.";
RL Insect Biochem. Mol. Biol. 38:1036-1045(2008).
RN [3] {ECO:0000313|EnsemblMetazoa:NP_001036939.1}
RP IDENTIFICATION.
RC STRAIN=p50T (Dazao) {ECO:0000313|EnsemblMetazoa:NP_001036939.1};
RG EnsemblMetazoa;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the replication factor A protein 2 family.
CC {ECO:0000256|ARBA:ARBA00007815}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB194777; BAD69790.1; -; mRNA.
DR RefSeq; NP_001036939.1; NM_001043474.1.
DR AlphaFoldDB; Q5TLD2; -.
DR SMR; Q5TLD2; -.
DR EnsemblMetazoa; NM_001043474.1; NP_001036939.1; GeneID_692485.
DR GeneID; 692485; -.
DR KEGG; bmor:692485; -.
DR CTD; 6118; -.
DR OrthoDB; 72010at2759; -.
DR Proteomes; UP000005204; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd04478; RPA2_DBD_D; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR004365; NA-bd_OB_tRNA.
DR InterPro; IPR040260; RFA2-like.
DR InterPro; IPR014646; Rfa2/RPA32.
DR InterPro; IPR014892; RPA_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR13989:SF16; REPLICATION PROTEIN A 32 KDA SUBUNIT; 1.
DR PANTHER; PTHR13989; REPLICATION PROTEIN A-RELATED; 1.
DR Pfam; PF08784; RPA_C; 1.
DR Pfam; PF01336; tRNA_anti-codon; 1.
DR PIRSF; PIRSF036949; RPA32; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000005204}.
FT DOMAIN 60..136
FT /note="OB"
FT /evidence="ECO:0000259|Pfam:PF01336"
FT DOMAIN 167..251
FT /note="Replication protein A C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08784"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 259 AA; 29234 MW; ADBA12BCEB3A69E9 CRC64;
MWNDDPSGGG FLNTTNQFGN TATPKKTGRR AARTAPIVIR QALHSGEEGV KIWGTEIQIV
SIVARIRSIR MQSTKITYTI QDITGRMRAV LWLDQEAMEV EDTSSPKVQV NDYIQIYGNV
KTNKGTKVLM AFKIMPVTDV NIITFHYFQC IHNKIQMEAG SKKEKNIQDV PINNMLPANS
MVGITETSSV NGLNSRQMMV FNLIRGSTVE QGISKQDMYA SLKDRMTKVE FENILEWMCG
EGHIYSTIDE EHFRATDAF
//
