ID Q5UYW7_HALMA Unreviewed; 198 AA.
AC Q5UYW7;
DT 07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT 07-DEC-2004, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=DNA binding protein putative transcriptional regulator {ECO:0000313|EMBL:AAV47536.1};
DE SubName: Full=TetR/AcrR family transcriptional regulator {ECO:0000313|EMBL:QCP92234.1};
GN OrderedLocusNames=rrnAC2777 {ECO:0000313|EMBL:AAV47536.1};
GN ORFNames=E6P14_15710 {ECO:0000313|EMBL:QCP92234.1};
OS Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS B-1809) (Halobacterium marismortui).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=272569 {ECO:0000313|EMBL:AAV47536.1, ECO:0000313|Proteomes:UP000001169};
RN [1] {ECO:0000313|EMBL:AAV47536.1, ECO:0000313|Proteomes:UP000001169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43049 {ECO:0000313|EMBL:AAV47536.1}, and ATCC 43049 / DSM
RC 3752 / JCM 8966 / VKM B-1809 {ECO:0000313|Proteomes:UP000001169};
RX PubMed=15520287; DOI=10.1101/gr.2700304;
RA Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA Hood L., Ng W.V.;
RT "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT Dead Sea.";
RL Genome Res. 14:2221-2234(2004).
RN [2] {ECO:0000313|EMBL:QCP92234.1, ECO:0000313|Proteomes:UP000298722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43049 {ECO:0000313|EMBL:QCP92234.1,
RC ECO:0000313|Proteomes:UP000298722};
RA DasSarma S., DasSarma P., DasSarma S., Fomenkov A., Vincze T., Anton B.P.,
RA Roberts R.J.;
RT "Methylomes of two halophilic Archaea, Haloarcula marismortui and Haloferax
RT mediterranei.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AY596297; AAV47536.1; -; Genomic_DNA.
DR EMBL; CP039138; QCP92234.1; -; Genomic_DNA.
DR RefSeq; WP_011224422.1; NZ_CP039138.1.
DR AlphaFoldDB; Q5UYW7; -.
DR STRING; 272569.rrnAC2777; -.
DR PaxDb; 272569-rrnAC2777; -.
DR EnsemblBacteria; AAV47536; AAV47536; rrnAC2777.
DR GeneID; 40153632; -.
DR KEGG; hma:rrnAC2777; -.
DR PATRIC; fig|272569.17.peg.3352; -.
DR eggNOG; arCOG02646; Archaea.
DR HOGENOM; CLU_069356_15_3_2; -.
DR Proteomes; UP000001169; Chromosome I.
DR Proteomes; UP000298722; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR47506:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR LMRA; 1.
DR PANTHER; PTHR47506; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000001169};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 4..64
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 27..46
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 198 AA; 22191 MW; EA9DACF53F6F3E53 CRC64;
MDDGDTADDI MDATYRALCT HGYADLTMQD IADESDKSKA ALHYHYDSKH DLLCAFLEYL
YDGFVDRIED PAGETPHERL LSLIDSVLDK PDDGSEEFGT AILEIRAHAP YEPGFRERLT
KFDDYLVDEL EVILEDGIAD GTFKSDLDAD ETAQFIVTVL TGAATERVTT GRPVKCTRRM
LTEYVETHLL DGQQEVTA
//
