ID Q5X011_LEGPL Unreviewed; 392 AA.
AC Q5X011;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=Membrane fusion protein biotin-lipoyl like domain-containing protein {ECO:0000259|Pfam:PF13533};
GN OrderedLocusNames=lpl0218 {ECO:0000313|EMBL:CAH14447.1};
OS Legionella pneumophila (strain Lens).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=297245 {ECO:0000313|EMBL:CAH14447.1, ECO:0000313|Proteomes:UP000002517};
RN [1] {ECO:0000313|EMBL:CAH14447.1, ECO:0000313|Proteomes:UP000002517}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lens {ECO:0000313|EMBL:CAH14447.1,
RC ECO:0000313|Proteomes:UP000002517};
RX PubMed=15467720; DOI=10.1038/ng1447;
RA Cazalet C., Rusniok C., Bruggemann H., Zidane N., Magnier A., Ma L.,
RA Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J.,
RA Glaser P., Buchrieser C.;
RT "Evidence in the Legionella pneumophila genome for exploitation of host
RT cell functions and high genome plasticity.";
RL Nat. Genet. 36:1165-1173(2004).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR628337; CAH14447.1; -; Genomic_DNA.
DR AlphaFoldDB; Q5X011; -.
DR KEGG; lpf:lpl0218; -.
DR LegioList; lpl0218; -.
DR HOGENOM; CLU_018816_14_5_6; -.
DR Proteomes; UP000002517; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..94
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
SQ SEQUENCE 392 AA; 44073 MW; BF4ED9B7749C9B50 CRC64;
MKIMNLNLKK LIGYFLIIVI FFSVVLWFLS HQGISVERAK VKYDHFIQYI EDDAKTRAIK
IYSIVSPVSG ELLRINLTEG DKVKKDDVIA TIKSKIPALL DIRAKQELEH ELGTAEALYE
QAKAESIRAE AALETAHSDF KRKEPLAKKG FVSETELEHA QLEYQLRQKE HNAALRKLHA
AEHYILKVKA SLSASEGSEA IQQDKIEIRS PVTGSILRVI EKSSTTVESG TKIMDIADVV
GLEVVADILS DDAAKIPPYA RVIIKRWGGP YPLEGRVRIV EPSGYTKVSA LGVEEQRVNV
IIDITTPYEL WKNLGDGYRV DVEIILFESN HALVVPMSAL FRDGEDWAVF VVKGHRAYKK
KLTIKYHNPD YAVIESGLEL GDEVTLSQFF NS
//
