ID Q5YF58_ISKNV Unreviewed; 1168 AA.
AC Q5YF58;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
OS Rock bream iridovirus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Iridoviridae; Alphairidovirinae; Megalocytivirus;
OC Infectious spleen and kidney necrosis virus.
OX NCBI_TaxID=263891 {ECO:0000313|EMBL:AAT71844.1, ECO:0000313|Proteomes:UP000125745};
RN [1] {ECO:0000313|EMBL:AAT71844.1, ECO:0000313|Proteomes:UP000125745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RBIV-KOR-TY1 {ECO:0000313|EMBL:AAT71844.1};
RX PubMed=15246274; DOI=10.1016/j.virol.2004.05.008;
RA Do J.W., Moon C.H., Kim H.J., Ko M.S., Kim S.B., Son J.H., Kim J.S.,
RA An E.J., Kim M.K., Lee S.K., Han M.S., Cha S.J., Park M.S., Park M.A.,
RA Lee J.S., Kim Y.C., Choi D.L., Kim J.W., Park J.W.;
RT "Complete genomic DNA sequence of rock bream iridovirus.";
RL Virology 325:351-363(2004).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
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DR EMBL; AY532606; AAT71844.1; -; Genomic_DNA.
DR Proteomes; UP000125745; Genome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279};
KW Reference proteome {ECO:0000313|Proteomes:UP000125745};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 183..464
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
SQ SEQUENCE 1168 AA; 129346 MW; 405EF2A39618EB73 CRC64;
MDIGRFVFGM YTADDVLNTS VVEITKAALK QEPGALYDPK LGPFMLPSDD EPVYDQRCVT
CDSVTCPGHF GHIELAQDVI LHYKECVAFL RVICHSCGAH VPGTRFESAL RRLPPQHIQC
QVCGLYQPVV RCGSSVTDPA YIVTEDYCGA SHVHSDVEYA RSVFQRVTPQ TLAIVGPKLT
HPLNLIMKRF MVLPSCCRPP NKVGGSMVHD DLTLLISYIV KRNLKLAAAT SPEQRILYYQ
ALKGDILCYM DNSKGRAVHV TSNKSLMGIK ECITKKGGLL RHNLMGKRRN YTARSVVGPE
STLALDQVGV PPQVADTLTI EEPVTKYNIE HVRQMRATGH LKALYDVDGQ VRHVVRCGLT
LHRSLRDGDV VVLNRQPTLH RNSMLGMRVK VLPGNTIRVN LAVTHGFNMD FDGDEGNLYL
PRSLSARAEV ATLMSPYTNI LSDCSKGVEV LLVQDTVLAL YMMSMWPHTR LEQQFVSMCC
MAVGVYHHRI CTAGDLFRLM VPEGFTWRRY GIVFVNGHLA DNSGPVTKRA LSGGYNSIIR
TMALHRGQKA AGRFIDCAQF VAREWLSWFP FSMGLDDMVV PGARNTAEAX YRHHMMLMES
ARDEIEVVSI LESIKNTLMA IPLAPTCMSV MTSAGSKGDA FNIMQISMLL GQQYVDGMRV
QREIDYGYRS LPHYKPVEVH SVEAKYESRG FVRSSFMDGL NPREAFFHAK CGREGMISTS
QMTGVTGYAE RRMVKFSEDL RIANDLSVRD ANGNIVQLLY GGHGMDPMMC WQDGCPVNFE
RMAMQIDQSL DICMMIPMDM AQAAQSVCER LAPIFPPLVR DSVMERHARI IKQGAAQFPC
SDADRWAQEV YDAYVRALCV PGSPVGIVCA QAFGARQTQS TLNIFHKAGG LHDTGSIRFG
ELLNLSKKSS RRLLYVHALG EQTLSSVKDV LGNAFFKGPL QDFVVDSTDD GVYTFNRAAL
FDRRIDMCHV LNEISSKHGS CCTIEQLSQY VIKIQRCSDA DGYLAGVFVG GAPTICNVHF
VFNNNKWVAV VSGSTLLYAL GVQGVDVDNT ACNNVWDVYE AKGLIAAKRF LTHSMVECLG
DDVHMAHIRV LVDRMTFSGL PTAVDRYTMR SCETGPISKA TFEESLDILV SSAVRGERDN
NTGVGACLVA GKMLPLGTGS CRVATDYL
//
