ID Q5ZQM7_SALSA Unreviewed; 225 AA.
AC Q5ZQM7;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=MHC class II antigen alpha chain {ECO:0000313|EMBL:CAD27719.1};
DE Flags: Fragment;
GN Name=DAA {ECO:0000313|EMBL:CAD27719.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:CAD27719.1};
RN [1] {ECO:0000313|EMBL:CAD27719.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12185536; DOI=10.1007/s00251-002-0477-1;
RA Stet R.J.M., de Vries B., Mudde K., Hermsen T.T., van Heerwaarden J.,
RA Shum B.P., Grimholt U.;
RT "Unique haplotypes of co-segregating major histocompatibility class II A
RT and class II B alleles in Atlantic salmon (Salmo salar) give rise to
RT diverse class II genotypes.";
RL Immunogenetics 54:320-331(2002).
RN [2] {ECO:0000313|EMBL:CAD27719.1}
RP NUCLEOTIDE SEQUENCE.
RA Stet R.J.;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AJ438965; CAD27719.1; -; mRNA.
DR AlphaFoldDB; Q5ZQM7; -.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR001003; MHC_II_a_N.
DR PANTHER; PTHR19944:SF86; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00993; MHC_II_alpha; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00920; MHC_II_alpha; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 2: Evidence at transcript level;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW MHC II {ECO:0000256|ARBA:ARBA00023182};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 196..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 87..182
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAD27719.1"
SQ SEQUENCE 225 AA; 24642 MW; 9D9F93867F5C19AB CRC64;
CWQVYAEHKV LHIDLYISGC SDSDGLDMYG LDGEEMWYAD FNKGEGVVAL PPFADPFTFP
GFYEGAVGNQ GVCKANLAVN IKAYKNPEEK IDPPHSSIYP RDDVDLGVEN TLICHVSGFH
PAPVRVRWTR NNQNLTEGVR LSTPYPNADF TLNQFSSLPF TPEEGDIYGC TVEHKGLAEP
LTRIWEPEVI QPSVGPAVFC GVGLTVGLLG VAAGTFFLIK GNQCN
//
