ID Q5ZTT3_LEGPH Unreviewed; 630 AA.
AC Q5ZTT3;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=TraD {ECO:0000313|EMBL:AAU28144.1};
GN OrderedLocusNames=lpg2078 {ECO:0000313|EMBL:AAU28144.1};
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624 {ECO:0000313|EMBL:AAU28144.1, ECO:0000313|Proteomes:UP000000609};
RN [1] {ECO:0000313|EMBL:AAU28144.1, ECO:0000313|Proteomes:UP000000609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513
RC {ECO:0000313|Proteomes:UP000000609};
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
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DR EMBL; AE017354; AAU28144.1; -; Genomic_DNA.
DR RefSeq; YP_096091.1; NC_002942.5.
DR AlphaFoldDB; Q5ZTT3; -.
DR STRING; 272624.lpg2078; -.
DR PaxDb; 272624-lpg2078; -.
DR KEGG; lpn:lpg2078; -.
DR PATRIC; fig|272624.6.peg.2173; -.
DR eggNOG; COG3505; Bacteria.
DR HOGENOM; CLU_016763_2_0_6; -.
DR OrthoDB; 9803543at2; -.
DR Proteomes; UP000000609; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014128; T4SS_TraD.
DR InterPro; IPR019476; T4SS_TraD_DNA-bd.
DR NCBIfam; TIGR02759; TraD_Ftype; 1.
DR PANTHER; PTHR37937; CONJUGATIVE TRANSFER: DNA TRANSPORT; 1.
DR PANTHER; PTHR37937:SF1; CONJUGATIVE TRANSFER: DNA TRANSPORT; 1.
DR Pfam; PF10412; TrwB_AAD_bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000609};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 170..554
FT /note="Type IV secretion system coupling protein TraD DNA-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF10412"
SQ SEQUENCE 630 AA; 71138 MW; D535010E0B90D9E1 CRC64;
MMAVNPTKLF IRGGQIFLHN VRMFTQVGKK VSLAMLIVFF IFSVIAFYFN TSAYQRYIGQ
QWVKAQAMTL IQSKAKQVVR MPTGESYPVY SAQIVKAPMV IGIVNQLKQA LLKSMIEALF
ASVMMLIVMV KWLQKRGENQ SKAKIIRGSE LVDENTLQKC IKKTSRISPY RIGGVSLPFG
SETQHIQIVG TTGSGKTVAI RDLLTTIQAR GERAIIYDKG GTYLSRFYRE HQDVILNPLD
TRGHSWNVWA ECEDKADLEA LAEAIMPMPI NNTMDPFWIK AARMIFVSTA NELKNDPKRS
NLMLLQYLLT ADLGRIHHLL RHTESESLVS DKVQKTALNV KTVMATYLKS LLYLKDDGDI
FSIRDWILNE QNNSCLFVSS DGRKHPTIRP LISAWINTAT KELLSLAPDD NRRVWFILDE
LATLHALPFL AAVKSESRKF GGCFLLGHHG ASQLRTIYGN DGAASLSNLC STRLFLRLPE
HTDAEHASRN IGTYEIEEVN ESISYGANTM RDGISVSRQT KEKQLVLPTQ IQVINDLQGY
LRVKGEFPAA KIKLNYVDYP LIHEEFIARD IDPDPLRQKV EQLVDTYSDP ILAASHDDAL
EAATSTKKDI TKPIAREKKL EEEKELVEFL
//
