ID Q63M56_BURPS Unreviewed; 688 AA.
AC Q63M56;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:CAH38266.1};
GN OrderedLocusNames=BPSS0805 {ECO:0000313|EMBL:CAH38266.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH38266.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH38266.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH38266.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
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DR EMBL; BX571966; CAH38266.1; -; Genomic_DNA.
DR RefSeq; WP_004551535.1; NZ_CP009537.1.
DR RefSeq; YP_110815.1; NC_006351.1.
DR AlphaFoldDB; Q63M56; -.
DR STRING; 272560.BPSS0805; -.
DR KEGG; bps:BPSS0805; -.
DR PATRIC; fig|272560.51.peg.7068; -.
DR eggNOG; COG5001; Bacteria.
DR Proteomes; UP000000605; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR005330; MHYT_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF03707; MHYT; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50924; MHYT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Reference proteome {ECO:0000313|Proteomes:UP000000605};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU00244}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 46..70
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 140..159
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT DOMAIN 5..198
FT /note="MHYT"
FT /evidence="ECO:0000259|PROSITE:PS50924"
FT DOMAIN 287..420
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 429..684
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 688 AA; 74358 MW; FE370EE2C9C7FF6C CRC64;
MHGTYNLWLV ALSLAVATLA SYTALDLSGR IALLAHGRLR HAWLAGSAVA MGIGIGSMHV
IGVLSVTLPI RIGFDAAITG LSLALAIVVS GFALYTIAGA QLTRLRLGIG GVLMGLGIAG
MHYTGDAAMR MKPAIEYDPL LFTASIVIAL VASTVALWIA QTLIGIGRSR LARIGAAGVM
GAAITGMHYT AYAAAIFAPG STCGAATGID LRWLAATVAL FTVAILIVAL ILSHFDVRTT
LLAGSVSRLS GQIVRMAAFD TLTDLPNRHT LNEHLGRALA AARARGGKLA ILFMDLDGFK
TINDSLGHPA GDEVLKTFSQ RLLRCVRDGD IVARLGGDEF VVLLESVSSD DEAARVARNV
LERMRKGRWN DGQALQVTPS IGIALYPKDG DTADTLLRHA DAAMYAAKRS GRCTYRFFEA
TMDEAAARAL KLQHALHEAL DSDYFSLCFQ PKFRCDGHRL AGAEALLRLN HPTLGKLAPM
EFIPVAERSG QIIEIGYWVI RETCRHLRRW RSAHRAACRI AINLSPRQLA QPDLVANILE
IVRAEHVEPR QLMFEITESV AMEDPPRTIE MIRLFQAHGF EIAIDDFGTG YSSLAYLQRF
GAKQLKIDRF FTHALDEQGH EGGAIVSAII ALAHSLAMDV VAEGVETRSQ LDRLKTLMCD
EIQGFLLGRP VPPEEFEAMV PLHSEAPA
//
