ID Q63TP3_BURPS Unreviewed; 300 AA.
AC Q63TP3;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:CAH35923.1};
GN OrderedLocusNames=BPSL1923 {ECO:0000313|EMBL:CAH35923.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH35923.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH35923.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH35923.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; BX571965; CAH35923.1; -; Genomic_DNA.
DR RefSeq; WP_004193481.1; NZ_CP009538.1.
DR RefSeq; YP_108523.1; NC_006350.1.
DR AlphaFoldDB; Q63TP3; -.
DR STRING; 272560.BPSL1923; -.
DR GeneID; 56595464; -.
DR KEGG; bps:BPSL1923; -.
DR PATRIC; fig|272560.51.peg.4067; -.
DR eggNOG; COG0583; Bacteria.
DR Proteomes; UP000000605; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08440; PBP2_LTTR_like_4; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30419; HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD; 1.
DR PANTHER; PTHR30419:SF14; LYSR FAMILY TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000605}.
FT DOMAIN 3..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 300 AA; 32487 MW; EB49B9B321933799 CRC64;
MNITLRQLRV FIEVARLKSF SRAGDEIGLT QSAVSRSVRE LEGEIGLKLI DRTTRDVQLT
DVGTNLIASV SRLLGDLDDA LREIREIGEQ RRGRVIVAAS PTIACRLMPR VVAACERRFP
FVTLGLRDDV QSDVLRKVKS GEVDFGVVIG PLATSELISE PLMTDSFCLV ARADHPLAAR
DRVPWTALAG ERLVLLDYAS GSRPLIDAAL AAHRVAAGVV QELGHSATVF GLVEAGVGVS
VLPWLSLPLP AGSSLVARPL APRAERTVEL VRRRDRSLSP AADAVWGLVK EMPARVEDLN
//
