ID Q63UZ1_BURPS Unreviewed; 303 AA.
AC Q63UZ1;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CAH35455.1};
GN OrderedLocusNames=BPSL1453 {ECO:0000313|EMBL:CAH35455.1};
OS Burkholderia pseudomallei (strain K96243).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH35455.1, ECO:0000313|Proteomes:UP000000605};
RN [1] {ECO:0000313|EMBL:CAH35455.1, ECO:0000313|Proteomes:UP000000605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K96243 {ECO:0000313|EMBL:CAH35455.1,
RC ECO:0000313|Proteomes:UP000000605};
RX PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT pseudomallei.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; BX571965; CAH35455.1; -; Genomic_DNA.
DR RefSeq; WP_004521296.1; NZ_CP009538.1.
DR RefSeq; YP_108075.1; NC_006350.1.
DR AlphaFoldDB; Q63UZ1; -.
DR STRING; 272560.BPSL1453; -.
DR GeneID; 56529178; -.
DR KEGG; bps:BPSL1453; -.
DR PATRIC; fig|272560.51.peg.3480; -.
DR eggNOG; COG0583; Bacteria.
DR Proteomes; UP000000605; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08422; PBP2_CrgA_like; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000605}.
FT DOMAIN 1..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 303 AA; 34029 MW; 6C30FE7BE7227A27 CRC64;
MDRYKQIETF VRVADAGSLA AAALEEGVSP VVLGRRIDAL EKRLGVKLMY RSTRRLVVSE
DGAAFLERCR GLLTEWAQAE NEVVAGRRAV GGHLIVSAPA AFGRKHVAPL APAFVADKPD
LQMSFNLTDR VVDLVREGYD LSIRIGGAVD PNFVAVKLAS NRRVVCGTPE YFRRHGRPRT
LDDLASHNCL AFNLQGGQNR GWYFRRNGKL VTMRVSGTLD CNDGELLHRW VSEGLGLGWR
STWEIAQQLA RGELETVLDE YALPDYDILA VYPQQRYVPA RVRYFIDYLR DVYARPGYWE
GAE
//
