ID Q64SV0_BACFR Unreviewed; 226 AA.
AC Q64SV0;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN OrderedLocusNames=BF2679 {ECO:0000313|EMBL:BAD49429.1};
OS Bacteroides fragilis (strain YCH46).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=295405 {ECO:0000313|EMBL:BAD49429.1, ECO:0000313|Proteomes:UP000002197};
RN [1] {ECO:0000313|EMBL:BAD49429.1, ECO:0000313|Proteomes:UP000002197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YCH46 {ECO:0000313|EMBL:BAD49429.1,
RC ECO:0000313|Proteomes:UP000002197};
RX PubMed=15466707; DOI=10.1073/pnas.0404172101;
RA Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N.,
RA Kuhara S., Hattori M., Hayashi T., Ohnishi Y.;
RT "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions
RT regulating cell surface adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; AP006841; BAD49429.1; -; Genomic_DNA.
DR RefSeq; WP_011202973.1; NC_006347.1.
DR RefSeq; YP_099963.1; NC_006347.1.
DR AlphaFoldDB; Q64SV0; -.
DR STRING; 295405.BF2679; -.
DR KEGG; bfr:BF2679; -.
DR PATRIC; fig|295405.11.peg.2591; -.
DR HOGENOM; CLU_018816_11_0_10; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000002197; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.170; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF26; TRANSPORT PROTEIN COMB; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 86..167
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 226 AA; 25277 MW; C211B286A2335658 CRC64;
MDAANTSNPS DKKKFIWLVI LLIIAIVVAV VWWWNYRKYV STIDANLDGS RVNVSVRAMA
PLSAVFKQEG DSVKRGELLA VLDSTMTEDY RIVSPVDGLI AKQWVVPGDL LQPGENIFTL
NEGKKLWVTV YLQETKFDEV RMGQQALFTL DAYLGLTFYG KIFYIGANTA SEFSLIPPDN
ASGNYTKVAQ RIPLKISIDR VEGKEKLKVN LRLLSGMSAN VKIVKE
//
