ID Q65DC3_BACLD Unreviewed; 1052 AA.
AC Q65DC3; Q62NU4;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Lantibiotic modifying enzyme {ECO:0000313|EMBL:AAU25567.1};
GN Name=lanM2 {ECO:0000313|EMBL:AAU25567.1};
GN OrderedLocusNames=BL00948 {ECO:0000313|EMBL:AAU25567.1};
OS Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=279010 {ECO:0000313|EMBL:AAU25567.1, ECO:0000313|Proteomes:UP000000606};
RN [1] {ECO:0000313|EMBL:AAU25567.1, ECO:0000313|Proteomes:UP000000606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB
RC 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46
RC {ECO:0000313|Proteomes:UP000000606};
RX PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA Rasmussen M.D., Andersen J.T., Jorgensen P.L., Larsen T.S., Sorokin A.,
RA Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT "Complete genome sequence of the industrial bacterium Bacillus
RT licheniformis and comparisons with closely related Bacillus species.";
RL Genome Biol. 5:R77.1-R77.12(2004).
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DR EMBL; CP000002; AAU25567.1; -; Genomic_DNA.
DR RefSeq; WP_003186383.1; NC_006322.1.
DR AlphaFoldDB; Q65DC3; -.
DR STRING; 279010.BL00948; -.
DR KEGG; bli:BL00948; -.
DR PATRIC; fig|279010.13.peg.4208; -.
DR eggNOG; COG4403; Bacteria.
DR HOGENOM; CLU_009398_1_1_9; -.
DR Proteomes; UP000000606; Chromosome.
DR GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR CDD; cd04792; LanM-like; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR InterPro; IPR007822; LANC-like.
DR InterPro; IPR025410; Lant_dehyd.
DR InterPro; IPR017146; Lanti_2_LanM.
DR NCBIfam; TIGR03897; lanti_2_LanM; 1.
DR PANTHER; PTHR12736; LANC-LIKE PROTEIN; 1.
DR PANTHER; PTHR12736:SF7; LANC-LIKE PROTEIN 3; 1.
DR Pfam; PF13575; DUF4135; 1.
DR Pfam; PF05147; LANC_like; 1.
DR PIRSF; PIRSF037228; Lant_mod_RumM; 1.
DR PRINTS; PR01950; LANCSUPER.
DR SMART; SM01260; LANC_like; 1.
DR SUPFAM; SSF158745; LanC-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000606}.
FT DOMAIN 189..561
FT /note="Lantibiotic biosynthesis protein dehydration"
FT /evidence="ECO:0000259|Pfam:PF13575"
SQ SEQUENCE 1052 AA; 119075 MW; E77F4783BB517FD2 CRC64;
MNEKSAGYHE RLPVAQTQSP LVNDKIKYWR SLFGDDDKWL NKAVSLLSHD PLSSIAQSSV
SQSVGLKDSR RGPWQKMQKR IFETPFSYKD SALQDSELLF DSLLTRFASA AQDALEEQNI
ILSPPLCRQV LTHLKQTLLQ IAHQTLILEL NILRLEDQLK GDTPEMRYLD FNDNFLVNPG
YLRTLFNEYP VLLRLLCTKT DYWVQNFSEL WKRLRQDREQ LQAAFHIAGD PVHIELGVGD
SHNKGKMAAI LTYSDGKKIV YKPRSHDVDD AFQLLLSWIN DRNSGSPLKT LRLINKKRYG
WSEFIPHETC HTKKELEGYY TRLGKLLAVL YSIDAVDFHH ENIIASGEHP VLIDLESIFH
QYKKRDEPGS TAVDKANYIL SRSVRSTGIL PFNLYFGRKN RDKVVDISGM GGQEAQESPF
QALQIKGFFR DDIRLEHDRF EIGEAKNLPT LDHQHVPVAD YLHCIIEGFS AVYRLISDHG
ESYLATIEHF KNCTVRNILK PTAHYASLLN KSYHPDFLRD AVDREVFLCR VEKFEDADTD
IAAAKTELKE LIRGDIPYFL SKPSDTYLLN GEEEPIAAYF ETPSFTRVIK KISSFSDQDL
KEQANVIRMS ILAAYNARHE KDAIDIDQNH PSPRSGALQP LAIAEKAADD LAEKRIEGND
GKDVTWISTV IEGVEEISWT ISPVSLDLYN GNAGIGLFMS YLSRFAKRPE TYSHITEQCV
FAIQRALNEL KEKEEFLKYA DSGAFTGVSG YLYFLQHAGT VQKKNEWIEL IHEALPVLEA
VIEQDENCDI ISGSAGALMV LMSLYEQLDD PVFLKLAEKC AGHLLQHKTN IENGAAWKDP
HTQNYYTGFA HGTSGIAAAL SRFNKVFDSQ SLKKIISQCL AFEKQLYIAS EKNWGSKGRE
QLSVAWCHGA AGILLSRSIL RENGVNDPGL HTDILNALET TVKHGLGNNR SFCHGDFGQL
EILRGFREEF SELNTIIQNT EDRLLTYFQE NPFSKGVSRG VDSAGLMLGL SGVGYGMLQC
QYGEELPELL QLSPPQALIK KNSKAFKREN VF
//
