ID Q65I25_BACLD Unreviewed; 320 AA.
AC Q65I25; Q62TH3;
DT 25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Heptaprenyl diphosphate synthase component II {ECO:0000313|EMBL:AAU23936.1};
GN Name=hepT {ECO:0000313|EMBL:AAU23936.1};
GN OrderedLocusNames=BL02782 {ECO:0000313|EMBL:AAU23936.1};
OS Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=279010 {ECO:0000313|EMBL:AAU23936.1, ECO:0000313|Proteomes:UP000000606};
RN [1] {ECO:0000313|EMBL:AAU23936.1, ECO:0000313|Proteomes:UP000000606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB
RC 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46
RC {ECO:0000313|Proteomes:UP000000606};
RX PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA Rasmussen M.D., Andersen J.T., Jorgensen P.L., Larsen T.S., Sorokin A.,
RA Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT "Complete genome sequence of the industrial bacterium Bacillus
RT licheniformis and comparisons with closely related Bacillus species.";
RL Genome Biol. 5:R77.1-R77.12(2004).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP000002; AAU23936.1; -; Genomic_DNA.
DR RefSeq; WP_003182996.1; NC_006322.1.
DR AlphaFoldDB; Q65I25; -.
DR STRING; 279010.BL02782; -.
DR GeneID; 66215588; -.
DR KEGG; bli:BL02782; -.
DR PATRIC; fig|279010.13.peg.2440; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_2_0_9; -.
DR Proteomes; UP000000606; Chromosome.
DR Bgee; BL02782; Expressed in skin epidermis and 5 other cell types or tissues.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR014119; GerC3_HepT.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR NCBIfam; TIGR02748; GerC3_HepT; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF87; OCTAPRENYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000000606};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 320 AA; 36397 MW; ADD5120A30558B92 CRC64;
MKLTTFYSFL NDDIELIEKE LEKTVHSDYP LLSEASLHLL QAGGKRIRPV FVLLSGMFGE
YDISKIKNVA VSLELIHMAS LVHDDVIDDA ELRRGQPTIK AKWDNRIAMY TGDYLFARSL
EAMTKINEPK AHEILSKAIV EVCLGEIEQI KDKYNMEQNL RTYLRRIRRK TALLIASSCQ
LGAIAAGAGE NIHKTLYWFG YYVGMSYQII DDILDFTSSE KELGKPVGSD LLQGNVTLPV
LYARKSPELK ARLMLVNSET TPEQIKPVIE ELKKTDAIEQ SFRVSEMYLN KAFELLETLP
KNRARTALGQ IAKYIGKRKF
//
