ID Q66BR7_YERPS Unreviewed; 570 AA.
AC Q66BR7;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=Flagellar M-ring protein {ECO:0000256|ARBA:ARBA00017949, ECO:0000256|PIRNR:PIRNR004862};
DE Flags: Precursor;
GN Name=fliF {ECO:0000313|EMBL:CAH20942.1};
GN OrderedLocusNames=YPTB1703 {ECO:0000313|EMBL:CAH20942.1};
OS Yersinia pseudotuberculosis serotype I (strain IP32953).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=273123 {ECO:0000313|EMBL:CAH20942.1, ECO:0000313|Proteomes:UP000001011};
RN [1] {ECO:0000313|EMBL:CAH20942.1, ECO:0000313|Proteomes:UP000001011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP32953 {ECO:0000313|Proteomes:UP000001011};
RX PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA Derbise A., Hauser L.J., Garcia E.;
RT "Insights into the evolution of Yersinia pestis through whole-genome
RT comparison with Yersinia pseudotuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC -!- FUNCTION: The M ring may be actively involved in energy transduction.
CC {ECO:0000256|ARBA:ARBA00003820, ECO:0000256|PIRNR:PIRNR004862}.
CC -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC organelle and consists of four rings (L,P,S, and M) mounted on a
CC central rod. The M ring is integral to the inner membrane of the cell
CC and may be connected to the flagellar rod via the S ring. The S
CC (supramembrane ring) lies just distal to the M ring. The L and P rings
CC lie in the outer membrane and the periplasmic space, respectively.
CC {ECO:0000256|ARBA:ARBA00025936}.
CC -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body
CC {ECO:0000256|ARBA:ARBA00004117, ECO:0000256|PIRNR:PIRNR004862}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FliF family. {ECO:0000256|ARBA:ARBA00007971,
CC ECO:0000256|PIRNR:PIRNR004862}.
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DR EMBL; BX936398; CAH20942.1; -; Genomic_DNA.
DR RefSeq; WP_011192181.1; NZ_CP009712.1.
DR AlphaFoldDB; Q66BR7; -.
DR GeneID; 66841863; -.
DR KEGG; ypo:BZ17_797; -.
DR KEGG; yps:YPTB1703; -.
DR PATRIC; fig|273123.14.peg.845; -.
DR Proteomes; UP000001011; Chromosome.
DR GO; GO:0009431; C:bacterial-type flagellum basal body, MS ring; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR013556; Flag_M-ring_C.
DR InterPro; IPR000067; FlgMring_FliF.
DR InterPro; IPR006182; FliF_N_dom.
DR InterPro; IPR043427; YscJ/FliF.
DR NCBIfam; TIGR00206; fliF; 1.
DR PANTHER; PTHR30046; FLAGELLAR M-RING PROTEIN; 1.
DR PANTHER; PTHR30046:SF0; FLAGELLAR M-RING PROTEIN; 1.
DR Pfam; PF01514; YscJ_FliF; 1.
DR Pfam; PF08345; YscJ_FliF_C; 1.
DR PIRSF; PIRSF004862; FliF; 1.
DR PRINTS; PR01009; FLGMRINGFLIF.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|PIRNR:PIRNR004862};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000313|EMBL:CAH20942.1};
KW Cilium {ECO:0000313|EMBL:CAH20942.1};
KW Flagellum {ECO:0000313|EMBL:CAH20942.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..223
FT /note="Flagellar M-ring N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01514"
FT DOMAIN 255..447
FT /note="Flagellar M-ring C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08345"
FT REGION 276..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 570 AA; 61624 MW; D8F241170A9CF6B0 CRC64;
MNASITGGEN RENTFTMTLA RLRANPKIPL LIAAAAAIAI IVALMLWAKS PDYRVLYSNL
SDRDGGDIVT QLTQLNIPYR FADNGGALLI PAEKVHETRL RLAQQGLPKG GAVGFELLDQ
EKFGISQFSE QINYQRALEG ELSRTIGTLG PVLNVRVHLA MPKPSLFVRE QKSPTASVTL
ALQPGRALDD GQINAIVYMV SSSVAGLPPG NVTVVDQTGR LLTQSDSAGR DLNASQLKFT
SEVENRYQRR IENILAPMVG NGNVHAQVTA QVDFASREQT DEEYKPNQAA NQGAVRSQQV
STSEQLGGTN VGGVPGALSN QPPVAPIAPI EIPQPAGAAA NNAAPANAAT TANANTTATA
AKASSSNSRH DQTTNFEVDR TIRHTQQQAG MVQRLSVAVV VNYTSDKAGK PIALSKDQLA
QVESLTREAM GFSTVRGDTL NVVNTPFTAS DDTRGSSLPF WQQQSFFDQL LNAGRYLLIL
LVAWILWRKL LRPMLAKKQV ADKAAASVNN IVQTAQAAET VKQSKEELAL RKKNQQRVSA
EVQAQRIREL ADKDPRVVAL VIRQWMSNDQ
//
