ID Q66EX6_YERPS Unreviewed; 360 AA.
AC Q66EX6;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Putative lipoprotein, heavy metal/multidrug efflux, MFP family {ECO:0000313|EMBL:CAH19805.1};
DE Flags: Precursor;
GN OrderedLocusNames=YPTB0565 {ECO:0000313|EMBL:CAH19805.1};
OS Yersinia pseudotuberculosis serotype I (strain IP32953).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=273123 {ECO:0000313|EMBL:CAH19805.1, ECO:0000313|Proteomes:UP000001011};
RN [1] {ECO:0000313|EMBL:CAH19805.1, ECO:0000313|Proteomes:UP000001011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP32953 {ECO:0000313|Proteomes:UP000001011};
RX PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA Derbise A., Hauser L.J., Garcia E.;
RT "Insights into the evolution of Yersinia pestis through whole-genome
RT comparison with Yersinia pseudotuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; BX936398; CAH19805.1; -; Genomic_DNA.
DR RefSeq; WP_002209199.1; NZ_CP009712.1.
DR AlphaFoldDB; Q66EX6; -.
DR GeneID; 66843017; -.
DR KEGG; ypo:BZ17_1996; -.
DR KEGG; yps:YPTB0565; -.
DR PATRIC; fig|273123.14.peg.2121; -.
DR Proteomes; UP000001011; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF20; LIPOPROTEIN-RELATED; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000313|EMBL:CAH19805.1};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 59..248
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 360 AA; 39910 MW; DE342DD5015EA46B CRC64;
MKIKTVVTLL ITFLLAACDR TPPETVESVR PVKIFMVEDS GQNGTRYFPA RLQAGDETQL
SFKRGGQLQE LLVREGEQVK KGQKIAMLND TDLSLRVRDR QSTFNLARDQ FNRFNTLQGR
SAVSRADLDI RRAEMESAQA ALDIARKELS DATIIAPFDG IIANVNVRNH QVMAAGQPVA
TLSALDTLDV VFSVPERLFT TLDISNRNYK PTVLLNHMPG REFIAEYKEH TTSTTSASQT
FQVTLTMKRP ADMPLLSGIS GRVRINSGNL SGTDHPTIIV PVEAVFNPDH AQLNDARVWV
IKNDNDQMHV EERKVQVGQL VENGIQVTSG LADGEQIVAA GTGELRPQQV VRAWVRERGL
//
