ID Q66FL4_YERPS Unreviewed; 682 AA.
AC Q66FL4;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=Putative type-III secretion protein, EscV/SsaV/LcrD {ECO:0000313|EMBL:CAH19562.1};
DE Flags: Precursor;
GN OrderedLocusNames=YPTB0322 {ECO:0000313|EMBL:CAH19562.1};
OS Yersinia pseudotuberculosis serotype I (strain IP32953).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=273123 {ECO:0000313|EMBL:CAH19562.1, ECO:0000313|Proteomes:UP000001011};
RN [1] {ECO:0000313|EMBL:CAH19562.1, ECO:0000313|Proteomes:UP000001011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP32953 {ECO:0000313|Proteomes:UP000001011};
RX PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA Derbise A., Hauser L.J., Garcia E.;
RT "Insights into the evolution of Yersinia pestis through whole-genome
RT comparison with Yersinia pseudotuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835}.
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DR EMBL; BX936398; CAH19562.1; -; Genomic_DNA.
DR RefSeq; WP_011191574.1; NZ_CP009712.1.
DR AlphaFoldDB; Q66FL4; -.
DR GeneID; 66843261; -.
DR KEGG; ypo:BZ17_2246; -.
DR KEGG; yps:YPTB0322; -.
DR PATRIC; fig|273123.14.peg.2379; -.
DR Proteomes; UP000001011; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR InterPro; IPR006302; T3SS_HrcV.
DR NCBIfam; TIGR01399; hrcV; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR PANTHER; PTHR30161:SF3; SECRETION SYSTEM APPARATUS PROTEIN SSAV; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 682 AA; 75446 MW; 42ED69FFEDD259DA CRC64;
MSKSALVRGL TMITARQDIF LAVMLLVAVF MMILPLPTTM VDLLIAINLA FSVILLMISI
YLRDPLEFSV FPSLLLITTL YRLALTISTT RLVLLQHDAG EIVEAFGQFV VGGNLAVGMI
IFTIITVVQF IVITKGSERV AEVSARFSLD GMPGKQMSID GDMRAGAIDS VEAKRLRERV
QKESRLFGAM DGAMKFVKGD AIAGIIVILV NIIGGITIGV MQHKMSAEEA MNTYAVLSIG
DGLCAQIPSL LISITAGIIV TRVPGSNKQS LANELAVQVG RQPDALWLAA AILTVFALLP
GFPFLIFITL AAAVAAPAFL LYRKNRRISQ DGRANGGGEE GAATGQRMTP GAVPLMLHCA
SNLHHPHLGR DIDGLRWRWF EHLGVPLPEV EIRCDPTLAE NTLSVQVYQE RVLEVVLPPD
SLLLTRPCSS LVTNNQALGA KMGSFDWLDA KQAMQARTLG IPYVEGHQRI ITCLTRVFER
YTAEFIGVQE TRYLMDAMEG RYGELVKELQ RQIPVGKVAE ILQRLVEENI SIRDLRTIFG
ALVVWAPKEK DIVMLTEYVR IALRRHLCRR FSHNKTWISV LRLGDGVEHL IRDSIRQTSS
GTYSALEERQ SLLILNKIKN AFAENQDAVL LTTLDVRRFV RKIIERDLFV LPVLSWQELG
DEMNLKVAGT IELIGDELDE TA
//
