ID Q66IM8_XENLA Unreviewed; 254 AA.
AC Q66IM8;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=C-reactive protein {ECO:0000256|ARBA:ARBA00040546};
GN Name=MGC86526 {ECO:0000313|EMBL:AAH81284.1,
GN ECO:0000313|RefSeq:NP_001087823.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH81284.1};
RN [1] {ECO:0000313|RefSeq:NP_001087823.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH81284.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Liver {ECO:0000313|EMBL:AAH81284.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001087823.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01172}.
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DR EMBL; BC081284; AAH81284.1; -; mRNA.
DR RefSeq; NP_001087823.1; NM_001094354.1.
DR DNASU; 447647; -.
DR GeneID; 447647; -.
DR KEGG; xla:447647; -.
DR OrthoDB; 4219275at2759; -.
DR Proteomes; UP000186698; Chromosome 8S.
DR Bgee; 447647; Expressed in lung and 12 other cell types or tissues.
DR GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR030476; Pentaxin_CS.
DR InterPro; IPR001759; Pentraxin-related.
DR PANTHER; PTHR45869:SF7; C-REACTIVE PROTEIN; 1.
DR PANTHER; PTHR45869; C-REACTIVE PROTEIN-RELATED; 1.
DR Pfam; PF00354; Pentaxin; 1.
DR PRINTS; PR00895; PENTAXIN.
DR SMART; SM00159; PTX; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS00289; PTX_1; 1.
DR PROSITE; PS51828; PTX_2; 1.
PE 2: Evidence at transcript level;
KW Acute phase {ECO:0000256|ARBA:ARBA00022486};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..254
FT /note="C-reactive protein"
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001087823.1"
FT /id="PRO_5033206956"
SQ SEQUENCE 254 AA; 28884 MW; 89F2E56DFBCF5A45 CRC64;
MEMRVLCLLL IAGSMAQEDM DRNVFFFSKK SDADYVVLTP MVAEPLNKLT VCSRSYTGGG
TYTLLNVGTP ELRISDMFVI YLTTSGYNQI SPYFTTTIIA NNSWVSMTAK ADVLDWMHIC
MTWDSNTRVL QLWVNGKVYP RTVLQKGSSI DLHHSIVLGQ KQRKTRASHT RNYVYQWDTG
SLFQGEISDV HMWNEVLSPE TIRKVLLNDR EINGNVISWR SLNYTIIGDV IVQPKLQCRY
GSESGSSYSQ CSMD
//
