ID Q66S07_OIKDI Unreviewed; 343 AA.
AC Q66S07;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 13-SEP-2023, entry version 78.
DE SubName: Full=Zinc-binding alcohol dehydrogenase-like protein {ECO:0000313|EMBL:AAT47884.1};
GN ORFNames=008-47 {ECO:0000313|EMBL:AAT47884.1}, GSOID_T00002099001
GN {ECO:0000313|EMBL:CBY19948.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:AAT47884.1};
RN [1] {ECO:0000313|EMBL:AAT47884.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15343333; DOI=10.1038/nature02709;
RA Seo H.C., Edvardsen R.B., Maeland A.D., Bjordal M., Jensen M.F., Hansen A.,
RA Flaat M., Weissenbach J., Lehrach H., Wincker P., Reinhardt R.,
RA Chourrout D.;
RT "Hox cluster disintegration with persistent anteroposterior order of
RT expression in Oikopleura dioica.";
RL Nature 431:67-71(2004).
RN [2] {ECO:0000313|EMBL:AAT47884.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15649342; DOI=10.1016/j.cub.2004.12.010;
RA Edvardsen R.B., Seo H.C., Jensen M.F., Mialon A., Mikhaleva J., Bjordal M.,
RA Cartry J., Reinhardt R., Weissenbach J., Wincker P., Chourrout D.;
RT "Remodelling of the homeobox gene complement in the tunicate Oikopleura
RT dioica.";
RL Curr. Biol. 15:R12-R13(2005).
RN [3] {ECO:0000313|EMBL:CBY19948.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY613856; AAT47884.1; -; Genomic_DNA.
DR EMBL; FN653133; CBY19948.1; -; Genomic_DNA.
DR AlphaFoldDB; Q66S07; -.
DR InParanoid; Q66S07; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08288; MDR_yhdh; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR014188; Acrylyl-CoA_reductase_AcuI.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR NCBIfam; TIGR02823; oxido_YhdH; 1.
DR PANTHER; PTHR43677:SF1; ACRYLYL-COA REDUCTASE ACUI-RELATED; 1.
DR PANTHER; PTHR43677; SHORT-CHAIN DEHYDROGENASE/REDUCTASE; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT DOMAIN 24..339
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 343 AA; 35716 MW; F8AEF29CD7CF1064 CRC64;
MRAKSVRAFR ALVTTAKKTP AVVQSLSAAD LPDISQVKGE EGACSVHVKV KYSNVNYKDA
LVAQGLYAGL PLPMVGGIDL TGTVMSDSSG KFKEGDKIIV NGFGIGTDHF GGFAEEAKVR
PEWCQSLPAG MSHLTAARIG TAGYTASLCV EAIRQTVKPS EGPIAVSGAT GGVGSVSVSL
LSNLGYEVHA ISGKTEQNAE FLTALGAHTV LNRSEFEVKP RALGKERFAG AVDACGSNVL
ANILSMTKRY GTVSACGLAA GLDLPTSVAP FILRGIILNG VECVYLPISK RESAYDLLSN
ACPESDLDLI GRNPIISLEE VPVVAKAMLS GEITGRYVVD PSA
//
