ID Q68FC6_MOUSE Unreviewed; 592 AA.
AC Q68FC6;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 24-JAN-2024, entry version 101.
DE SubName: Full=Wrd43 protein {ECO:0000313|EMBL:AAH79913.1};
DE Flags: Fragment;
GN Name=Wdr43 {ECO:0000313|MGI:MGI:1919765};
GN Synonyms=Wrd43 {ECO:0000313|EMBL:AAH79913.1};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH79913.1};
RN [1] {ECO:0000313|EMBL:AAH79913.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6 {ECO:0000313|EMBL:AAH79913.1};
RC TISSUE=Head {ECO:0000313|EMBL:AAH79913.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the UTP5 family.
CC {ECO:0000256|ARBA:ARBA00038335}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC079913; AAH79913.1; -; mRNA.
DR AlphaFoldDB; Q68FC6; -.
DR PeptideAtlas; Q68FC6; -.
DR AGR; MGI:1919765; -.
DR MGI; MGI:1919765; Wdr43.
DR ChiTaRS; Wdr43; mouse.
DR GO; GO:0005730; C:nucleolus; IEA:UniProt.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007148; SSU_processome_Utp12.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44267; WD REPEAT-CONTAINING PROTEIN 43; 1.
DR PANTHER; PTHR44267:SF1; WD REPEAT-CONTAINING PROTEIN 43; 1.
DR Pfam; PF04003; Utp12; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 2: Evidence at transcript level;
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT REPEAT 37..72
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 386..488
FT /note="Small-subunit processome Utp12"
FT /evidence="ECO:0000259|Pfam:PF04003"
FT REGION 496..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..567
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAH79913.1"
SQ SEQUENCE 592 AA; 66324 MW; D47E43F3F89D7A2C CRC64;
EVTGTKDQAD LLALGTAVGS ILLYSTVRGE LHSKLTSGGH ENRVNCIQWH QDNDCLYSCS
DDKYIVEWST QTCKVKCKWK GDNSSVSSLC ISPDGKMLLS AGRTIKLWVL ETKEVYRHFT
GHATPVSSLR FTTIRPNESQ PSDGITGLYF LSGAVHDRLL NVWQVRSENK EKSAVMSFTV
TDEPVYVDLT LSENKEEPVK LAVVCRDGQV HLFEHILNGH CKKPLTSNCT IQIATPGKGK
KVTPKPIPIL AASFCLDKMS LLLVYGNWFQ PTIERVALNS KDTHICLERD ISNCWAPTVE
TAITKVKTPV MNSEAKVLVP GIPGHHAPIK LPPAQPKEAE NKRKLGSTEA TIEERLGAMD
LDRKGRKDDL QTNSFAVLLT QGLESNDFEI LNKVLQTKNV NLIKRTVLRI PLRVVIPLLQ
ELTKRLQGHP NSAALMIQWL KCVLTIHASY LSTLPDLVEQ LGTLYQLMES RVKTFQKLSN
LHGKLILLVT QVTASEKSKK MTSPGQKAKL VYEEESSEEE SDDEVPEKDS DDNWDEDEDK
DSEKDEGVDE DNEEEDEDME DKEENEEDRE VSSEKELNGD SDLDPENESE EE
//
