ID Q68FR4_RAT Unreviewed; 412 AA.
AC Q68FR4;
DT 11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT 11-OCT-2004, sequence version 1.
DT 03-MAY-2023, entry version 94.
DE SubName: Full=Zmiz2 protein {ECO:0000313|EMBL:AAH79401.1};
DE Flags: Fragment;
GN Name=Zmiz2 {ECO:0000313|EMBL:AAH79401.1, ECO:0000313|RGD:1309256};
GN Synonyms=RGD1309256 {ECO:0000313|RGD:1309256};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|EMBL:AAH79401.1};
RN [1] {ECO:0000313|EMBL:AAH79401.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis {ECO:0000313|EMBL:AAH79401.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; BC079401; AAH79401.1; -; mRNA.
DR RefSeq; NP_001093977.1; NM_001100507.1.
DR AlphaFoldDB; Q68FR4; -.
DR GeneID; 289783; -.
DR KEGG; rno:289783; -.
DR UCSC; RGD:1309256; rat.
DR AGR; RGD:1309256; -.
DR CTD; 83637; -.
DR RGD; 1309256; Zmiz2.
DR OrthoDB; 20246at2759; -.
DR PhylomeDB; Q68FR4; -.
DR Genevisible; Q68FR4; RN.
DR GO; GO:0043596; C:nuclear replication fork; ISO:RGD.
DR GO; GO:0005634; C:nucleus; ISO:RGD.
DR GO; GO:0030374; F:nuclear receptor coactivator activity; ISO:RGD.
DR GO; GO:0061665; F:SUMO ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISO:RGD.
DR GO; GO:0016925; P:protein sumoylation; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10782:SF38; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 77..163
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 224..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAH79401.1"
SQ SEQUENCE 412 AA; 44183 MW; CD091C31298A3EA3 CRC64;
PLYLKHVCQP GRNTIQITVT ACCCSHLFVL QLVHRPSVRS VLQGLLKKRL LPAEHCITKI
KRNFSSGTIP GTPGPNGEDG VEQTAIKVSL KCPITFRRIQ LPARGHDCRH IQCFDLESYL
QLNCERGTWR CPVCNKTALL EGLEVDQYML GILIYIQNSD YEEITIDPTC SWKPVPVKPD
LHIKEEPDGP VLKRCRTVSP AHVLMPSVME MIAALGPGAA PFAPLQPPSA PTPSDYPSQG
SNFLGPGTFP ESFPSATPAT PNLAEFTQGP PPISYQSDIP SSLLTPDKSA PCLPGQMAPA
GHLDPAHNPG PPGLHTPNLG PTPGTQLHHP NPSPASRQPL GQPNTGPISE LAFNPATGMM
GPPSMTGAGE ASEPALDLLP ELTNPDELLS YLGPPDLPTN SSDDLLSLFE NN
//
