ID Q6C4K1_YARLI Unreviewed; 606 AA.
AC Q6C4K1;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=YALI0E26081p {ECO:0000313|EMBL:CAG80012.1};
GN ORFNames=YALI0_E26081g {ECO:0000313|EMBL:CAG80012.1};
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591 {ECO:0000313|EMBL:CAG80012.1, ECO:0000313|Proteomes:UP000001300};
RN [1] {ECO:0000313|EMBL:CAG80012.1, ECO:0000313|Proteomes:UP000001300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150 {ECO:0000313|Proteomes:UP000001300};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ANKZF1/VMS1 family.
CC {ECO:0000256|ARBA:ARBA00009262}.
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DR EMBL; CR382131; CAG80012.1; -; Genomic_DNA.
DR RefSeq; XP_504411.1; XM_504411.1.
DR AlphaFoldDB; Q6C4K1; -.
DR STRING; 284591.Q6C4K1; -.
DR EnsemblFungi; CAG80012; CAG80012; YALI0_E26081g.
DR GeneID; 2912624; -.
DR KEGG; yli:YALI0E26081g; -.
DR VEuPathDB; FungiDB:YALI0_E26081g; -.
DR HOGENOM; CLU_014293_1_1_1; -.
DR InParanoid; Q6C4K1; -.
DR OMA; NTRRANY; -.
DR OrthoDB; 8371at2759; -.
DR Proteomes; UP000001300; Chromosome E.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IBA:GO_Central.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047139; ANKZ1/VMS1.
DR InterPro; IPR041175; VLRF1/Vms1.
DR PANTHER; PTHR16036; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16036:SF2; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF18826; bVLRF1; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000001300};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 191..348
FT /note="VLRF1"
FT /evidence="ECO:0000259|Pfam:PF18826"
FT REGION 81..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..562
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 67476 MW; 63A0453336E505E2 CRC64;
MAKAKQAPTA YFLYDLPESI LKSLKVYDFN GVLRSEETEV KPSSQFSAEE KAFHRYNHKL
RLQGLAAIRK PEYDQLLKDG LTDTQKDDDS DSNSNSNSNS NSNSEEDTES DSDEEFGLPR
KMELASISEA GDGETAKDEL KGSPVIFLKS PEVEPKTLTV YKNALGHVSP TESGILGEIQ
RVNTLPEATS VIIMAGGGHF AAAIFQHSPK IKNTMVPLIL ETKSFHRYTT RRSQGGSQSA
SDGSKGKAKS VGSSLRRYGE SQLQMEVKEL LTSPEWKKRL LPGLPTSAAN IYIRASGKGS
RGLVLGFEGC PIPKNDSRVK SIPFNTRRAN YTEVLRSWTE LSTVKVVDVS KEEEEAEKTR
EKEAEKARKE QSRLAAAEAK KQKQQQSQPT TVPLTPLMKQ TSEITELIRK SRAPKLISYL
KLQKLKSPYQ LEFPEGDKTG TLCPTALHYA AKEGSAYIVS VLLKQLGADP TVTNSFGKTA
WDLVSDSKTR DTFQLARGAL GEDKWDWKAS HVGEALTDEQ IEQRDKKEAA EHDQKVKQSI
AQQEEEQKEK ESSKRYEKIV AKSGLGKRLP QMATKLEDTR GLSDEAKMRL ERERRARAAE
ARFAKK
//
