ID Q6DJ21_XENTR Unreviewed; 538 AA.
AC Q6DJ21; A0A6I8PUX5;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 27-MAR-2024, entry version 128.
DE SubName: Full=Kelch like family member 7 {ECO:0000313|Ensembl:ENSXETP00000059020};
DE SubName: Full=Kelch-like 7 {ECO:0000313|EMBL:AAH75364.1};
DE SubName: Full=Kelch-like protein 7 {ECO:0000313|RefSeq:NP_001004916.1, ECO:0000313|RefSeq:XP_012819974.1};
GN Name=klhl7 {ECO:0000313|EMBL:AAH75364.1,
GN ECO:0000313|Ensembl:ENSXETP00000059020,
GN ECO:0000313|RefSeq:NP_001004916.1, ECO:0000313|RefSeq:XP_012819974.1,
GN ECO:0000313|Xenbase:XB-GENE-971613};
GN Synonyms=klhl6 {ECO:0000313|RefSeq:NP_001004916.1,
GN ECO:0000313|RefSeq:XP_012819974.1}, sbbi26
GN {ECO:0000313|RefSeq:NP_001004916.1,
GN ECO:0000313|RefSeq:XP_012819974.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH75364.1};
RN [1] {ECO:0000313|RefSeq:NP_001004916.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH75364.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole body {ECO:0000313|EMBL:AAH75364.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000059020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000059020};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000059020}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2020) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001004916.1, ECO:0000313|RefSeq:XP_012819974.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_012819974.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_012819974.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC075364; AAH75364.1; -; mRNA.
DR RefSeq; NP_001004916.1; NM_001004916.1.
DR RefSeq; XP_012819974.1; XM_012964520.3.
DR DNASU; 448292; -.
DR Ensembl; ENSXETT00000061087; ENSXETP00000059020; ENSXETG00000007392.
DR GeneID; 448292; -.
DR KEGG; xtr:448292; -.
DR AGR; Xenbase:XB-GENE-971613; -.
DR CTD; 55975; -.
DR Xenbase; XB-GENE-971613; klhl7.
DR HOGENOM; CLU_004253_14_2_1; -.
DR OMA; WRAASPM; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000008143; Chromosome 6.
DR Bgee; ENSXETG00000007392; Expressed in testis and 13 other cell types or tissues.
DR CDD; cd18447; BACK_KLHL7; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR047060; KLHL7_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF435; KELCH-LIKE PROTEIN 7; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 2: Evidence at transcript level;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 1..63
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 538 AA; 60796 MW; C5EE3D40BD8CD0D7 CRC64;
MVQDRKIPAH RVVLAAASHF FNLMFTTNML ESKSFEVELK DAEPDIIEQL VEFAYTARIS
VNSNNVQSLL DAANQYQIEP VKRMCVEFLK EQVDASNCLG ISVLAECLDC PELKATADDF
IHQHFTEVYK TDEFLQLDVK RVTHLLNQDT LTVRAEDQVY DAAVRWLKYD EPNRQPYMVD
ILAKVRFPLI SKNFLSKTVQ AEPLIQDNPE CLKMVISGMR YHLLSPEDRE ELVEGTRPRR
KKHDYRIALF GGSQPQSCRY FNPKDYNWSD IRCPFEKRRD AACVFWDNVV YILGGSQLFP
IKRMDCYNVV KDSWYSKLGP PTPRDSLAAC AAEGKIYTSG GSEVGNNALY LFECYDTRTE
SWHTKPSMLT QRCSHGMVEA NGLIYVCGGS LGNNVSGRVL NCCEVYDPAT ESWTELCPMI
EARKNHGLVF VKDKIFAIGG QNGLGGLDSV EYYDIKLNEW KMVSPMPWKG VTVKCAAVGS
VIYVLAGFQG VGRLGHILEY NTEADKWIAN SKVRAFPVTS CLICVVDTCG ANEETLET
//
