ID Q6DVB8_CARAU Unreviewed; 129 AA.
AC Q6DVB8;
DT 16-AUG-2004, integrated into UniProtKB/TrEMBL.
DT 16-AUG-2004, sequence version 1.
DT 03-MAY-2023, entry version 49.
DE SubName: Full=GABA-A receptor alpha 1 subunit {ECO:0000313|EMBL:AAT58232.1};
DE Flags: Fragment;
OS Carassius auratus (Goldfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Carassius.
OX NCBI_TaxID=7957 {ECO:0000313|EMBL:AAT58232.1};
RN [1] {ECO:0000313|EMBL:AAT58232.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:AAT58232.1};
RX PubMed=15869561; DOI=10.1111/j.1365-2826.2005.01311.x;
RA Martyniuk C.J., Crawford A.B., Hogan N.S., Trudeau V.L.;
RT "GABAergic modulation of the expression of genes involved in GABA synaptic
RT transmission and stress in the hypothalamus and telencephalon of the female
RT goldfish (Carassius auratus).";
RL J. Neuroendocrinol. 17:269-275(2005).
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DR EMBL; AY640225; AAT58232.1; -; mRNA.
DR AlphaFoldDB; Q6DVB8; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR InterPro; IPR001390; GABAAa_rcpt.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR PANTHER; PTHR18945:SF218; GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-2; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR PRINTS; PR01079; GABAARALPHA.
DR PRINTS; PR00252; NRIONCHANNEL.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
PE 2: Evidence at transcript level;
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAT58232.1}.
FT DOMAIN 3..129
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAT58232.1"
FT NON_TER 129
FT /evidence="ECO:0000313|EMBL:AAT58232.1"
SQ SEQUENCE 129 AA; 15054 MW; 48D4FCF228544159 CRC64;
WDGLLDGYDN RLRPGLGDRV TEVKTDIYVT SFGPVSDTDM EYTVDVFFRQ RWTDERLKFN
GPMNILRLNN LMASKIWTPD TFFHNGKKSV AHNMTMPNKL LRIMENGTLL YTMRLTVQAE
CPMQLEDFP
//
