ID Q6F9V3_ACIAD Unreviewed; 306 AA.
AC Q6F9V3;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 129.
DE RecName: Full=HTH-type transcriptional regulator MetR {ECO:0000256|ARBA:ARBA00019365};
GN Name=metR {ECO:0000313|EMBL:CAG69160.1};
GN OrderedLocusNames=ACIAD2384 {ECO:0000313|EMBL:CAG69160.1};
OS Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=62977 {ECO:0000313|EMBL:CAG69160.1, ECO:0000313|Proteomes:UP000000430};
RN [1] {ECO:0000313|EMBL:CAG69160.1, ECO:0000313|Proteomes:UP000000430}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33305 / BD413 / ADP1 {ECO:0000313|Proteomes:UP000000430};
RX PubMed=15514110; DOI=10.1093/nar/gkh910;
RA Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT a versatile and naturally transformation competent bacterium.";
RL Nucleic Acids Res. 32:5766-5779(2004).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CR543861; CAG69160.1; -; Genomic_DNA.
DR RefSeq; WP_004928238.1; NC_005966.1.
DR AlphaFoldDB; Q6F9V3; -.
DR STRING; 202950.GCA_001485005_00026; -.
DR GeneID; 45234697; -.
DR KEGG; aci:ACIAD2384; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_6; -.
DR OrthoDB; 155872at2; -.
DR BioCyc; ASP62977:ACIAD_RS10900-MONOMER; -.
DR Proteomes; UP000000430; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd08441; PBP2_MetR; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR037406; MetR_PBP2.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF25; HTH-TYPE TRANSCRIPTIONAL REGULATOR METR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Reference proteome {ECO:0000313|Proteomes:UP000000430};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 306 AA; 35080 MW; 84B9496D92DC6503 CRC64;
MLEIRHLKTL LALREHGSLV AAANDLCLTP SAISHQLKEL DHWYGVEVVN RRSRPVTFSN
VGQRLLKLAD DILPQIQIAQ SDITRIVHGQ TGRIVFSSEC HSCFDWLMPL LNQYRQQYPD
VDLDFASGFE ANPHDLLQTG EFDLLITADP IALKGIEYFP IFEYESRLVL SNTHPLVRAE
KVTVEELAEQ TLITYPVDKH RLDIMAHLFI PANIQPKEIR TTDLTQMLIQ LVASGRGISA
LPDWVVNEYE QKGWVTSRRL DCVSANGLRR TLYAGYRIEE KEKSYFEGFL KQLAKFSQKR
AHYYAN
//
