ID Q6FT40_CANGA Unreviewed; 753 AA.
AC Q6FT40;
DT 19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 92.
DE SubName: Full=Candida glabrata strain CBS138 chromosome G complete sequence {ECO:0000313|EMBL:CAG59531.1};
GN OrderedLocusNames=CAGL0G05588g {ECO:0000313|CGD:CAL0130659,
GN ECO:0000313|EMBL:CAG59531.1};
OS Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX NCBI_TaxID=284593 {ECO:0000313|EMBL:CAG59531.1, ECO:0000313|Proteomes:UP000002428};
RN [1] {ECO:0000313|EMBL:CAG59531.1, ECO:0000313|Proteomes:UP000002428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65
RC {ECO:0000313|Proteomes:UP000002428};
RX PubMed=15229592; DOI=10.1038/nature02579;
RG Genolevures;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA Wincker P., Souciet J.L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
RN [2] {ECO:0007829|PDB:3RMH}
RP X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 607-753.
RX PubMed=22025677; DOI=10.1128/MCB.05875-11;
RA Yu E.Y., Sun J., Lei M., Lue N.F.;
RT "Analyses of Candida Cdc13 orthologues revealed a novel OB fold dimer
RT arrangement, dimerization-assisted DNA binding, and substantial structural
RT differences between Cdc13 and RPA70.";
RL Mol. Cell. Biol. 32:186-198(2012).
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DR EMBL; CR380953; CAG59531.1; -; Genomic_DNA.
DR RefSeq; XP_446604.1; XM_446604.1.
DR PDB; 3RMH; X-ray; 1.90 A; A/B=607-753.
DR PDBsum; 3RMH; -.
DR AlphaFoldDB; Q6FT40; -.
DR SMR; Q6FT40; -.
DR STRING; 284593.Q6FT40; -.
DR EnsemblFungi; CAGL0G05588g-T; CAGL0G05588g-T-p1; CAGL0G05588g.
DR GeneID; 2888025; -.
DR KEGG; cgr:CAGL0G05588g; -.
DR CGD; CAL0130659; CAGL0G05588g.
DR VEuPathDB; FungiDB:CAGL0G05588g; -.
DR eggNOG; ENOG502QU50; Eukaryota.
DR HOGENOM; CLU_011303_0_0_1; -.
DR InParanoid; Q6FT40; -.
DR Proteomes; UP000002428; Chromosome G.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 2.40.50.810; -; 1.
DR Gene3D; 2.40.50.860; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR031749; Cdc13_N.
DR InterPro; IPR040650; Cdc13_OB2.
DR InterPro; IPR041028; Cdc13_OB4_dimer.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR011564; Telomer_end-bd_POT1/Cdc13.
DR Pfam; PF16853; CDC13_N; 1.
DR Pfam; PF18691; Cdc13_OB2; 1.
DR Pfam; PF18233; Cdc13_OB4_dimer; 1.
DR Pfam; PF02765; POT1; 1.
DR SMART; SM00976; Telo_bind; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3RMH};
KW Reference proteome {ECO:0000313|Proteomes:UP000002428}.
FT DOMAIN 417..575
FT /note="Telomeric single stranded DNA binding POT1/Cdc13"
FT /evidence="ECO:0000259|SMART:SM00976"
FT REGION 220..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 87034 MW; 9243858774FA20C6 CRC64;
MSIEIIAVLT SISKDDNGFH IALDDIAGEV RVLDIDEAQA REVVNECDLE VSDTNAFNIT
KIQLEKLCFV VAKCTSSGLQ LVNGDMTFKL QPVDVKVLDI NYIQENWNTL DKKKKDKISK
ILLALKKLDS DIKSEFNFVK LNNYKNTLVH FLSGIKMTKQ TKLTSFFTKQ TTMVESQNDF
NSQAMNTQQF TSQASIPGIS DDELIDSDDD LDNISEGSYP TVTRLGSTKH DLPTNHNGSS
ANKHSKKDSC LYVNFMDPHR NQLWTYNGDN SSVIISHCSL QSMSPVGFKS LDDLDKFTLR
LVFKQKTMVD ELLIPNNNCC EVVIKNKLEY METFGRLADT SSKLRKYLNG DLNITVKKWK
YEIRGYDSFK WTIEKLDFNP EMPVKEKVPE QGKCSNRYDF NSINFIDEST RDQVIQFKDM
IIEEENTAKF YIVFGYLLAC STDNSNYANF VFTDFTTNRK YEQKYTFDRY INDYNTKLDH
DQSFRVISYY NHFNEFNMKV KAKYGKDLNA MVNENSQIAD KNVSKYGILC RIVMKCKLYQ
SVLNLVERDI ELLDNLHELS IGEKPYIKEL FNKTEPYLTA SPTLNVNGDI ASSKTTRESK
EQVPCITDIT QYEVVEDHNI SQLNHLQHLT PKIYVLNVYI IDVEIVYDQE IRIKVVNELP
MVGKYVPPVD ILEVYITGKE EVQNFLGDEA LTMDIFTPLL NETSRLRVFQ RPSKTDRIIR
WSPIECTIQE LRLQRMFRLR DTIKVEETLS LTQ
//
