ID Q6JSR1_9MYRI Unreviewed; 728 AA.
AC Q6JSR1;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Elongation factor 2 {ECO:0000313|EMBL:AAQ77161.1};
DE Flags: Fragment;
OS Geophilus vittatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Chilopoda;
OC Pleurostigmophora; Geophilomorpha; Geophilidae; Geophilus.
OX NCBI_TaxID=118466 {ECO:0000313|EMBL:AAQ77161.1};
RN [1] {ECO:0000313|EMBL:AAQ77161.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15579388; DOI=10.1016/j.ympev.2004.09.005;
RA Regier J.C., Wilson H.M., Shultz J.W.;
RT "Phylogenetic analysis of Myriapoda using three nuclear protein-coding
RT genes.";
RL Mol. Phylogenet. Evol. 34:147-158(2005).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AY310259; AAQ77161.1; -; mRNA.
DR AlphaFoldDB; Q6JSR1; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR CDD; cd03700; EF2_snRNP_like_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF10; ELONGATION FACTOR 2; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 2: Evidence at transcript level;
KW Elongation factor {ECO:0000313|EMBL:AAQ77161.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:AAQ77161.1}.
FT DOMAIN 10..343
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAQ77161.1"
FT NON_TER 728
FT /evidence="ECO:0000313|EMBL:AAQ77161.1"
SQ SEQUENCE 728 AA; 81604 MW; E113700E0B4B3524 CRC64;
EIRGLMDRKR NIRNMSVIAH VDHGKSTLTD SLVGKAGIIA AQKAGEMRFT DTRKDEQERC
ITIKSTAISM YFEVEQKDLQ FITEESQKEK DTKGFLINLI DSPGHVDFSS EVTAALRVTD
GALVVVDCVS GVCVQTETVL RQAIAERIKP VLFMNKMDRA LLELQLEAED LFQTFQRIVE
NVNVIIATYG DETGPMGDVK VDPSRGNVGF GSGLHGWAFT LKQFSEMYAE KFKIDIDKLM
KKLWGDNFYN PKTKKWAKSR DDGGEYKRTF CMFILDPIYR VFEAIMGYKT TEIPKLLEKL
NITLKGEDKD KDGKALLKIV MRQWLPAGEA LLQMIAIHLP SPVTAQRYRM EMLYEGPHDD
EAAVAIKTCD PNGPLMMYIS KMVPTSDKGR FYAFGRVFAG TVSTGQKVRI MGPNYTPGKK
EDLYEKAIQR TILMMGRYTE AIEDVPSGNI CGLVGVDQFL VKTGTISTFK DAHNLRVMKF
SVSPVVRVAV EPKNPSELPK LVEGLKRLAK SDPMVQCIIE ESGEHIVAGA GELHLEICLK
DLEEDHACIP IKVSDPVVSY RETVSEESSI MCLAKSPNKH NRLFMKAQPM PEGLAEDIDK
GDVTARDDFK ARARYLTEKY DYDITEARKI WCFGPDGTGP NILVDCTKGV QYLNEIKDSV
VAGFQWATKE GVMAEENMRG VRFNIFDVTL HADAIHRGGG QIIPTARRVL YACILTAAPR
MMEPVYLC
//
