ID Q6JUE6_CHTFR Unreviewed; 377 AA.
AC Q6JUE6;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE RecName: Full=Elongation factor 1-alpha {ECO:0000256|RuleBase:RU000325};
DE Flags: Fragment;
OS Chthamalus fragilis (Acorn barnacle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Cirripedia; Thoracica; Thoracicalcarea; Balanomorpha; Chthamaloidea;
OC Chthamalidae; Chthamalus.
OX NCBI_TaxID=37709 {ECO:0000313|EMBL:AAQ88221.1};
RN [1] {ECO:0000313|EMBL:AAQ88221.1}
RP NUCLEOTIDE SEQUENCE.
RA Regier J.C.;
RT "EF-1alpha sequences from arthropods.";
RL Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982, ECO:0000256|RuleBase:RU000325}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249,
CC ECO:0000256|RuleBase:RU000325}.
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DR EMBL; AY305462; AAQ88221.1; -; mRNA.
DR AlphaFoldDB; Q6JUE6; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF170; ELONGATION FACTOR 1-ALPHA 2; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 2: Evidence at transcript level;
KW Elongation factor {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:AAQ88221.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000325};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000325};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:AAQ88221.1}.
FT DOMAIN 1..196
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAQ88221.1"
FT NON_TER 377
FT /evidence="ECO:0000313|EMBL:AAQ88221.1"
SQ SEQUENCE 377 AA; 41278 MW; 56BD70B8AFE373CC CRC64;
QQMGKGSFKY AWVLDKLKAE RERGITIDIA LWKFETSKYY VTIIDAPGHR DFIKNMITGT
SQADCAVLIV ASGVGEFEAG ISKNGQTREH ALLAYTLGVK QMIIGINKMD TTEPPYSEAR
YKEICTEVSA YIKKVGYDPK TVAFVPISGW HGDNMLEASD KMPWYKGWET TRKSGSNSGK
TLLEALDNIE PPSRPSDKPL RLPLQDVYKI GGIGTVPVGR VETGVLKPGM IVCFAPSGLT
TEVKSVEMHH ESLPEALPGD NVGFNVKNVS VKELRRGYVA SDSKNKPATG CEDFTAQVII
LNHPGTVSAG YTPVLDCHTA HIACRFADLQ QKVDRRTGKV TEEAPKSLKS GDAAIIKLMP
SKPMVVETFT DFPPLGR
//
