ID Q6LIB3_PHOPR Unreviewed; 327 AA.
AC Q6LIB3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Putaive pyruvate dehydrogenase E1 component, beta subunit {ECO:0000313|EMBL:CAG22967.1};
GN Name=EF1354 {ECO:0000313|EMBL:CAG22967.1};
GN OrderedLocusNames=PBPRB1095 {ECO:0000313|EMBL:CAG22967.1};
OS Photobacterium profundum (strain SS9).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=298386 {ECO:0000313|EMBL:CAG22967.1, ECO:0000313|Proteomes:UP000000593};
RN [1] {ECO:0000313|Proteomes:UP000000593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1253 / SS9 {ECO:0000313|Proteomes:UP000000593};
RX PubMed=15746425; DOI=10.1126/science.1103341;
RA Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA Bartlett D.H., Valle G.;
RT "Life at depth: Photobacterium profundum genome sequence and expression
RT analysis.";
RL Science 307:1459-1461(2005).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR378678; CAG22967.1; -; Genomic_DNA.
DR RefSeq; WP_011221157.1; NC_006371.1.
DR AlphaFoldDB; Q6LIB3; -.
DR STRING; 298386.PBPRB1095; -.
DR KEGG; ppr:PBPRB1095; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_6; -.
DR Proteomes; UP000000593; Chromosome 2.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Pyruvate {ECO:0000313|EMBL:CAG22967.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000593};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 327 AA; 35860 MW; E3459833B67BDC1C CRC64;
MADMTLLEAV NLALHHEMEH DPKVVVLGED VGDNGGVFRA TVGLKAKFGL KRVIDSPLAE
ALIGGVTVGM ASQGLRPVAE FQFQGFVFPA MEHLMCHAAR MRNRTRGRLI CPAVFRAPFG
GGIHAPEHHS ESIEALFAHI PGFKVVIPSS PQRAYGLLLA SIRCNDPVMF FEPKRIYRTV
KSYVNDNGKA LPLDTCFTLR KGRDLTLVTW GACVVESLQA ASTLSSQGIE VEVIDLASIK
PIDMATIIHS LEKTGRLLVV HEASKTCGVG AEILARTAEH AMCLLKAPPK RVTGMDTIMP
YYRNEDFFMI QEEDIVIAAR ELVEGWK
//
