ID Q6MZ73_MYCUA Unreviewed; 444 AA.
AC Q6MZ73;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 79.
DE RecName: Full=Mutator family transposase {ECO:0000256|RuleBase:RU365089};
GN OrderedLocusNames=MUP031c {ECO:0000313|EMBL:CAE46842.1};
OS Mycobacterium ulcerans (strain Agy99).
OG Plasmid pMUM001 {ECO:0000313|EMBL:CAE46842.1,
OG ECO:0000313|Proteomes:UP000000765}.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=362242 {ECO:0000313|Proteomes:UP000000765};
RN [1] {ECO:0000313|EMBL:CAE46842.1, ECO:0000313|Proteomes:UP000000765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Agy99 {ECO:0000313|Proteomes:UP000000765};
RC PLASMID=Plasmid pMUM001 {ECO:0000313|Proteomes:UP000000765};
RX PubMed=14736915; DOI=10.1073/pnas.0305877101;
RA Stinear T.P., Mve-Obiang A., Small P.L.C., Frigui W., Pryor M.J.,
RA Brosch R., Jenkin G.A., Johnson P.D.R., Davies J.K., Lee R.E.,
RA Adusumilli S., Garnier T., Haydock S.F., Leadlay P.F., Cole S.T.;
RT "Giant plasmid-encoded polyketide synthases produce the macrolide toxin of
RT Mycobacterium ulcerans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:1345-1349(2004).
RN [2] {ECO:0000313|Proteomes:UP000000765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Agy99 {ECO:0000313|Proteomes:UP000000765};
RC PLASMID=Plasmid pMUM001 {ECO:0000313|Proteomes:UP000000765};
RX PubMed=15758215; DOI=10.1099/mic.0.27674-0;
RA Stinear T.P., Pryor M.J., Porter J.L., Cole S.T.;
RT "Functional analysis and annotation of the virulence plasmid pMUM001 from
RT Mycobacterium ulcerans.";
RL Microbiology 151:683-692(2005).
CC -!- FUNCTION: Required for the transposition of the insertion element.
CC {ECO:0000256|ARBA:ARBA00002190, ECO:0000256|RuleBase:RU365089}.
CC -!- SIMILARITY: Belongs to the transposase mutator family.
CC {ECO:0000256|ARBA:ARBA00010961, ECO:0000256|RuleBase:RU365089}.
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DR EMBL; BX649209; CAE46842.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6MZ73; -.
DR KEGG; mul:MUP031c; -.
DR Proteomes; UP000000765; Plasmid pMUM001.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004803; F:transposase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006313; P:DNA transposition; IEA:UniProtKB-UniRule.
DR InterPro; IPR001207; Transposase_mutator.
DR NCBIfam; NF033543; transpos_IS256; 1.
DR PANTHER; PTHR33217:SF5; MUTATOR FAMILY TRANSPOSASE; 1.
DR PANTHER; PTHR33217; TRANSPOSASE FOR INSERTION SEQUENCE ELEMENT IS1081; 1.
DR Pfam; PF00872; Transposase_mut; 1.
DR PROSITE; PS01007; TRANSPOSASE_MUTATOR; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172,
KW ECO:0000256|RuleBase:RU365089};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU365089};
KW Plasmid {ECO:0000313|EMBL:CAE46842.1};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464,
KW ECO:0000256|RuleBase:RU365089};
KW Transposition {ECO:0000256|ARBA:ARBA00022578,
KW ECO:0000256|RuleBase:RU365089}.
SQ SEQUENCE 444 AA; 49172 MW; CAB9E5EF985EAF7E CRC64;
MMTKTVVAVQ PSQNHEDEAG AVAAIDVPSS RDVDELEVAR ELVRQAREAG VGLTGPGGLL
KAMTKTVIET ALDEELSEHL GYDRHDRAGY GNGNSRNGTR SKTVLTDACG SIEIDVPRDR
AGTFEPKIVE KRQRRLTDVD EVVLSLYARG LTTGEISAHF AHIYDAAVSK DTVSRITDRV
LEEMTAWHTR PLERVYAAVF IDALHVKIRD GQVGPRPVYA AVGVDLAGHR DVLGMWAGEG
DGESAKYWLA VLTELKNRGV ADIFFLVCDG LKGLPDSVSA VFPDTVVQTC IIHLIRGTFR
YAGRQHHTAI ARALKPIYTA VNAAAAAEAL DAFDTEWGHR YPAAIRLWRN AWNEFIPFLD
YDTEIRKVIC STNAIEWLNA RYRRAIRARG HFPTEQSALK CLYLVTRSLD PTGTGQKRWT
MRWKPALNAF AITFADRMPG SETT
//
