ID Q6NF84_CORDI Unreviewed; 1872 AA.
AC Q6NF84;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Surface-anchored membrane protein {ECO:0000313|EMBL:CAE50541.1};
GN OrderedLocusNames=DIP2010 {ECO:0000313|EMBL:CAE50541.1};
OS Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype
OS gravis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=257309 {ECO:0000313|EMBL:CAE50541.1, ECO:0000313|Proteomes:UP000002198};
RN [1] {ECO:0000313|EMBL:CAE50541.1, ECO:0000313|Proteomes:UP000002198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700971 / NCTC 13129 / Biotype gravis
RC {ECO:0000313|Proteomes:UP000002198};
RX PubMed=14602910; DOI=10.1093/nar/gkg874;
RA Cerdeno-Tarraga A.M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.,
RA Bentley S.D., Besra G.S., Churcher C., James K.D., De Zoysa A.,
RA Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S.,
RA Jagels K., Moule S., Quail M.A., Rabbinowitsch E., Rutherford K.,
RA Thomson N.R., Unwin L., Whitehead S., Barrell B.G.Parkhill.J.;
RT "The complete genome sequence and analysis of Corynebacterium diphtheriae
RT NCTC13129.";
RL Nucleic Acids Res. 31:6516-6523(2003).
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DR EMBL; BX248359; CAE50541.1; -; Genomic_DNA.
DR RefSeq; WP_010935501.1; NC_002935.2.
DR SMR; Q6NF84; -.
DR STRING; 257309.DIP2010; -.
DR KEGG; cdi:DIP2010; -.
DR PATRIC; fig|257309.4.peg.2004; -.
DR HOGENOM; CLU_236394_0_0_11; -.
DR Proteomes; UP000002198; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 2.60.40.1140; Collagen-binding surface protein Cna, B-type domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR046022; DUF5979.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR041033; Prealbumin-like.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF19407; DUF5979; 10.
DR Pfam; PF17802; SpaA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000002198};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1847..1868
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..285
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1839..1872
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
SQ SEQUENCE 1872 AA; 204615 MW; 013C5F721F0BAAB5 CRC64;
MSNLRTIKKR ASIPAALVAI LAMVMSIVLV PLIAAPSANA EPLPKKEFET CGGSVAISFD
LSNSLSASDV EKSKQAALEL VKSLKGSPYR FGIYTFASHS PAAGNKNFTP VSLANDDGYN
KVVAAINDIQ MPAIRENKKG SPNGGTNWEG GLQAIANDID RGIKYDAVYF ITDGQPTWDN
NGRNWLGTTT EVVELENAVT QAKLISDKGA KLIPVGIGQL SDDKPFDLYK PILPSEDDYY
WSRYPWKIDR SLTGKQMLEK ITSPGLEPII LPDYSTLPQR MGQQIFTGCF QIAKNIIDAD
GNVIENPAGW NFDITAAGVQ GIPPSIETDK NGQDTFAMKS INKESFKITI TERPTGDQKQ
NFRFKNARCQ RYSYGQAPTD IPIKTSDTSI TLTADTKSLI SCGFNNLPVV PVSVSKKVNV
NTPQLLEELN NQTFDFTYSC EKGANEKEIK GEIKGVHNGE SKEIGKVAVG TQCEIKEVTP
KVDDSRMKLS TTWSSENTTA DANQDNGTYR FKADTDAFKN KKTVLATAEN NYEAQTATIK
LTKTIINRDK IPATKLPEKF PVTYTCRYVP HPNARPEHGG LPETNPYFVD SKTVVVPRDG
SIEIGPFPVG TQCSFEETAR LDPNVQADAK IPGFSLKTEW NSNICFGNTI DNNSQDCSTN
SVWIPKPGQY SLNVENTYTR ELASVEIEKT VSGDASDLTN SHEFSFNLRC EDSGVEVYSQ
DNIVVKKDGR QVIENIPVDA NCTLSEKQPE QKGVDFVVPA PFHLRASTAG DIVKVVVDNT
AKRQVAPISI QKKVHKKDTF SPEISASIDA LTYSVVAECT VPGVETPRKV LKTVSDNQTV
EFGNFPVGTT CSFSELTEAP AGTEMSYKFA DGPEVTIEDS TPINKVLTNT FENARGELKV
TKKVLDGDMP QALVDQIPSS FTVNVACSIT GNHSITLQKD EQKAVPGVVA GESCTLSEEV
TPITGATHHK HWIKGELLEV ADSTDITINP NGSNAIRLEN HYETDAVSLE LTKRVRVIDQ
VGNDVNSELK NAVVRPEQPF LFRYRCEING QVVAENTLSA DAINTGATKV PRGSICTVEE
DSSSVELSNA TLSHVEFFVH GTKTNDKASV AINSDHNRLD ATNTFTLKTG SFNLKKKVDG
EGVSTIHEDR RFEISYRCTL GDWKKNGTIT LGRFDSAESH SVKDIPVGAS CEIIEDSEKA
QEPNAQVTAR WTHTDSTNGW GDTEAACENH AACEVDPKNE FATTVVIAGN EKENFQGTFI
VWNTYTYDKT KVEINKVLTN DGPELAGKDN FAFTLKCTDP RFAGSDLADK HSIPDPTITV
ALNAKGQSRA SYQVADERHD SVEVPVGYNC TVTENPIALY DAKATTQFSG PAVVENTAVQ
RTSSNSASAR FVTEKQENNG TQKIQVTNDY IRPRADVMVH KTIAKPEHSV DPWLLNTTYS
ITYKCDDPYI KDRSYSNDVD IQADAEKPTP IFADPTAHVK IPASAVCTFS ENTEGHLPGE
VKGVVDETNK VAEFAGEHEK RSYFTPEIKD VVLSESEPTR IEFTNSYVMP QRILSLQKYV
EGDPGHAVIA PEETFEFSYT CTMPHLFPNQ PNPMSQEVGN KVARGVIKIR EGETWRSPEV
PIGTSCTIKE EDDPALRTKL ENNALRMVPT YLFPTERAGA ASAPVIPPLT DRPIYNGTEP
RLQMPESGIE LNDAHSHTVV INNVYTTDAE INIAKVNADN SPLPGAHFAI YGIGENGQRK
ELPEVADAPA KSAKSVEQAL FAVRLRPGSY ELVETQAPQG GQLLPKPWRF DVKAANAGAI
GDLEVTLDNY DADSGLITVE HPQGKPWLIK VANVSASTLP LTGSNGYLRW LLAGAAGLLV
AAALWLVARR KR
//
