ID Q6NPB1_DROME Unreviewed; 409 AA.
AC Q6NPB1;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 22-FEB-2023, entry version 99.
DE SubName: Full=RH57813p {ECO:0000313|EMBL:AAR30175.1};
GN Name=Shc {ECO:0000313|EMBL:AAR30175.1};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAR30175.1};
RN [1] {ECO:0000313|EMBL:AAR30175.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Berkeley {ECO:0000313|EMBL:AAR30175.1};
RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M.,
RA Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.,
RA Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A.,
RA Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S.,
RA Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.;
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BT011015; AAR30175.1; -; mRNA.
DR AlphaFoldDB; Q6NPB1; -.
DR VEuPathDB; VectorBase:FBgn0015296; -.
DR HOGENOM; CLU_029532_0_1_1; -.
DR ExpressionAtlas; Q6NPB1; baseline and differential.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR CDD; cd01209; PTB_Shc; 1.
DR CDD; cd09925; SH2_SHC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006019; PID_Shc-like.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035676; SHC_SH2.
DR PANTHER; PTHR10337:SF11; DSHC PROTEIN; 1.
DR PANTHER; PTHR10337; SHC TRANSFORMING PROTEIN; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR PRINTS; PR00629; SHCPIDOMAIN.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50001; SH2; 1.
PE 2: Evidence at transcript level;
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 31..179
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 301..392
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 210..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 44977 MW; E7ACECE268F41D01 CRC64;
MPKNGDAGNR SGSGTTSDGC IYPDDVIMGV GVAFNVRYTG CVEVKTSMKS LDFETRTQLA
RECINRVCEA AGLKSAGKRR LTNFISDRPS MQHAGTNIII NVSSRALSLS NVETGEVIAN
HNMPRISFAS GGDNDTLDFL AYIAKNEDEW RACYVLECAG GQSEDLIVTI GKAFALRFNA
LSRLNDPSAD CNINQSCKEN VKEYYNDLPN KLPPEVPEPQ QQQVQQPLHP HAPRVAQLNL
KKPRDRLSSN LIDLNSPPPD QTTNKLGHFD PLQATTAANS VLPSVRDVFD GPQCPLTAEV
WFHAGISRPI SERLLQQDGD FLVRESQGKR GQYVLTGLEG KTPKHLLLID PEGVVRTKDR
IFDSISHLIN YHWAHALPII SEDSELVLRN PARRPQQDQA ASPITSASS
//
