ID Q6P2X2_XENTR Unreviewed; 318 AA.
AC Q6P2X2;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 119.
DE SubName: Full=Elongation factor 1-gamma {ECO:0000313|RefSeq:NP_989262.1};
DE SubName: Full=Eukaryotic translation elongation factor 1 gamma {ECO:0000313|Ensembl:ENSXETP00000062069};
GN Name=eef1g {ECO:0000313|Ensembl:ENSXETP00000062069,
GN ECO:0000313|RefSeq:NP_989262.1, ECO:0000313|Xenbase:XB-GENE-975013};
GN Synonyms=eef1g-a {ECO:0000313|RefSeq:NP_989262.1}, eef1g-b
GN {ECO:0000313|RefSeq:NP_989262.1}, ef1g
GN {ECO:0000313|RefSeq:NP_989262.1}, gig35
GN {ECO:0000313|RefSeq:NP_989262.1}, MGC76278
GN {ECO:0000313|EMBL:AAH64264.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH64264.1};
RN [1] {ECO:0000313|RefSeq:NP_989262.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH64264.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH64264.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000062069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000062069};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000062069}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2020) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_989262.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Probably plays a role in anchoring the complex to other
CC cellular components. {ECO:0000256|ARBA:ARBA00003468}.
CC -!- SUBUNIT: EF-1 is composed of four subunits: alpha, beta, delta, and
CC gamma. {ECO:0000256|ARBA:ARBA00011237}.
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DR EMBL; BC064264; AAH64264.1; -; mRNA.
DR RefSeq; NP_989262.1; NM_203931.1.
DR DNASU; 394875; -.
DR Ensembl; ENSXETT00000062850; ENSXETP00000062069; ENSXETG00000026372.
DR GeneID; 394875; -.
DR KEGG; xtr:394875; -.
DR AGR; Xenbase:XB-GENE-975013; -.
DR CTD; 1937; -.
DR Xenbase; XB-GENE-975013; eef1g.
DR HOGENOM; CLU_011226_3_1_1; -.
DR OMA; TQYFSWT; -.
DR OrthoDB; 159792at2759; -.
DR Proteomes; UP000008143; Chromosome 4.
DR Bgee; ENSXETG00000026372; Expressed in mesonephros and 33 other cell types or tissues.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd03181; GST_C_EF1Bgamma_like; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.30.70.1010; Translation elongation factor EF1B, gamma chain, conserved domain; 1.
DR InterPro; IPR001662; EF1B_G_C.
DR InterPro; IPR036433; EF1B_G_C_sf.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004046; GST_C.
DR PANTHER; PTHR43986; ELONGATION FACTOR 1-GAMMA; 1.
DR PANTHER; PTHR43986:SF1; ELONGATION FACTOR 1-GAMMA; 1.
DR Pfam; PF00647; EF1G; 1.
DR Pfam; PF00043; GST_C; 1.
DR SMART; SM01183; EF1G; 1.
DR SUPFAM; SSF89942; eEF1-gamma domain; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR PROSITE; PS50040; EF1G_C; 1.
DR PROSITE; PS50405; GST_CTER; 1.
PE 2: Evidence at transcript level;
KW Elongation factor {ECO:0000256|ARBA:ARBA00022768, ECO:0000256|PROSITE-
KW ProRule:PRU00519};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|PROSITE-
KW ProRule:PRU00519}; Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 1..101
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT DOMAIN 157..318
FT /note="EF-1-gamma C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50040"
FT REGION 101..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 36811 MW; 4C7C8F0F22B41508 CRC64;
MQYNKQATEQ AKEEIKAVLG VLDSHLKTRT FLVGERVTLA DIAVTCSLLW LYKQVLEPSF
RQPFGNVTRW FVTCVNQPEF RAVLGEVKLC DKMAQFDAKK FAEMQPKKET PKKEKPAKEP
KKEKEEKKKA TPAPAPAPAP EDDMDESEKA LAAEPKSKDP YAHLPKSSFV MDEFKRKYSN
EDTLAVALPY FWEHFDKEGW SIWYAEYKFP EELTQTFMSC NLITGMFQRL DKLRKTGFAS
VILFGTNNDS SISGVWVFRG QDLAFTLSED WQIDYESYTW RKLDSNSEEC KTLVKEYFCW
EGDFKHVGKA FNQGKIFK
//
