ID Q6PF43_XENLA Unreviewed; 793 AA.
AC Q6PF43;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=MGC68953 protein {ECO:0000313|EMBL:AAH57735.1};
DE SubName: Full=von Willebrand factor A domain containing 5A S homeolog {ECO:0000313|RefSeq:NP_001079962.1};
GN Name=vwa5a.S {ECO:0000313|RefSeq:NP_001079962.1,
GN ECO:0000313|Xenbase:XB-GENE-5898487};
GN Synonyms=loh11cr2a {ECO:0000313|RefSeq:NP_001079962.1}, vwa5a
GN {ECO:0000313|RefSeq:NP_001079962.1,
GN ECO:0000313|Xenbase:XB-GENE-5898487}, vwa5a.L
GN {ECO:0000313|RefSeq:NP_001079962.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH57735.1};
RN [1] {ECO:0000313|RefSeq:NP_001079962.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH57735.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH57735.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001079962.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC057735; AAH57735.1; -; mRNA.
DR RefSeq; NP_001079962.1; NM_001086493.1.
DR DNASU; 379653; -.
DR GeneID; 379653; -.
DR KEGG; xla:379653; -.
DR AGR; Xenbase:XB-GENE-5898487; -.
DR CTD; 379653; -.
DR Xenbase; XB-GENE-5898487; vwa5a.S.
DR OrthoDB; 909551at2759; -.
DR Proteomes; UP000186698; Chromosome 1S.
DR Bgee; 379653; Expressed in spleen and 18 other cell types or tissues.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013694; VIT.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR45737; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR PANTHER; PTHR45737:SF8; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR Pfam; PF08487; VIT; 1.
DR Pfam; PF13768; VWA_3; 1.
DR SMART; SM00609; VIT; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51468; VIT; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT DOMAIN 2..132
FT /note="VIT"
FT /evidence="ECO:0000259|PROSITE:PS51468"
FT DOMAIN 280..461
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 793 AA; 87313 MW; BFCDB4CD7A409491 CRC64;
MAPFCGLIIV CSRQPVPLRG ISVEVQVKGF VADVCATLKY KNTEEKPIEA VFVFPLDQDS
AVYSFEATVE GKKIVADLQE REQANKTYDE AISKGQQAFL LQEDKSSGDI FSCSVGNLPP
GQEAEVKLSF VQELPLESDG AVRFVLPAVL NPRYTPKDHE ESITAQVPRV PIGQIPYTLD
LTAHFYSAYG ISKIQSNCDI SPIEYTDSDK TAAKVSLGQG HKFERDVELL AYYTDVNKPS
VTAEAGLPDA KTDTLMADPA VMLNFYPSFP ATQEQSNCGE FLFLLDRSGS MECGMNSEPN
APQRIESAKE TLVLLLKSLP LGCYFNIIGF GSHFEFFFPE TIEYTQETMD EAVKKVNQIE
ANMGGTEILQ PLMKIYKTAV RPDHPRQLFV FTDGEVGNTK QVIEEVQRNA HNHRCFAFGI
GEGASTSLIK GISRAAGGTC EFITGKERMQ PKVLKALKNS LQPTVKQISL KWTLPSGVES
VLLSKPPSNI FQGHRAIVYA QLKGKISEGE EGEVSLEYKF KDEMFRNSLK FPLKVEKAER
PTIHRLGAKA QISELESGTN SESEEVKKRI IESSIQSGVI SSLTAFVAVN KETKTPVQGP
PVRRDIPTPG LMYGAPMACT MSMPASGFMF GCYMSADMAM PEMAHRGGGL RLQSKVSNKK
ARERLLAAPK FHSGPKFSVQ ANEAPALFRL ISLQKADGSW TLNSELASIL GLSLKEMRNN
DPKQSPDPAV WATLLAVIWL HAHCLDQRDE WELLEHKAVS WIKSRAGSSS LRDSIKAGND
LLKSAVDPEE FGL
//
