ID   Q6TW32_ORFV             Unreviewed;       787 AA.
AC   Q6TW32;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=ORF068 NTPase {ECO:0000313|EMBL:AAR98163.1};
OS   Orf virus (ORFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Parapoxvirus.
OX   NCBI_TaxID=10258 {ECO:0000313|EMBL:AAR98163.1, ECO:0000313|Proteomes:UP000122185};
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1] {ECO:0000313|EMBL:AAR98163.1, ECO:0000313|Proteomes:UP000122185}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OV-IA82 {ECO:0000313|EMBL:AAR98163.1};
RX   PubMed=14671098; DOI=10.1128/JVI.78.1.168-177.2004;
RA   Delhon G., Tulman E.R., Afonso C.L., Lu Z., de la Concha-Bermejillo A.,
RA   Lehmkuhl H.D., Piccone M.E., Kutish G.F., Rock D.L.;
RT   "Genomes of the parapoxviruses ORF virus and bovine papular stomatitis
RT   virus.";
RL   J. Virol. 78:168-177(2004).
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DR   EMBL; AY386263; AAR98163.1; -; Genomic_DNA.
DR   Proteomes; UP000122185; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR004968; DNA_primase/NTPase_C.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF03288; Pox_D5; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   4: Predicted;
FT   DOMAIN          479..641
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000259|PROSITE:PS51206"
SQ   SEQUENCE   787 AA;  88631 MW;  C1D853337F5414F4 CRC64;
     MAAPICDNSH VFLLKRLGVP SSCRRSEDPR FVEILTPFEL ANYIERHPGC CLFETLRDEE
     DCSVVRVFAD VDMDSVLEEE DFVAALEDLI VELAAFFDRF ASGSCGTVPG EVKRAMLANF
     SVTRSTAEHK TSFHLIFTET YTTLDTLVAA KRPLLDLCRR SDNVLLRALD TAVYRRGATL
     RVVGTRKTPE SSAVHCMQSP DDDIKDYLFT FVELSDASVY FELAEREQHT LSTVCWETSY
     IPFGDAMRRV CQAVVNDIVN LRDITEDNFL DTPLVIDYAT RCALCKKPKH KHAHHITMGN
     GCLRLVKGGN AHSCKVKIIQ LEGNRLFTAA QIIIASEVVK LTERNDYIVW LNNSWRFSAE
     ESLITKLILD VRHSLPADYA NDMLCPRKRK VVETNIRDML VDISETDTQY DKLPFTNGVL
     DLATGEFLTG DRAKACVCTV STGYAFSREE FAAAADSEAM RRLVGVIDDI QPDTPENADN
     RALYERAMSS ALCGATKTVI VFFYGDTMTG KSTSKRLLMS ALGGLFIETG QTVLTDVLDK
     GPNPFVANMH LRRAVFCSEL PDFACNNARK LRSDNFKKLT EPCIVGRPCF SNKIHNRNHA
     TFIIDTNYRP VFDRVDNALM RRVALVRFRT HFSSSATRAA AAHNVEYSAV KEMDESLDTK
     IQRNYFRYAF LRLLVQWFGK YHVPQVSLAP TPDAVPDFAF HRRVAELVVA SNDAHRRAME
     SLSKLGYVLV GGNVAMPADA FRQRLAAHFN ARVHGGDIDA FMFKHKKVVN VTEEYVEYVF
     IEDVENK
//