ID   Q6V1V4_DROSI            Unreviewed;       360 AA.
AC   Q6V1V4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Cact {ECO:0000313|EMBL:AAQ64891.1};
DE   Flags: Fragment;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240 {ECO:0000313|EMBL:AAQ64891.1};
RN   [1] {ECO:0000313|EMBL:AAQ64891.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Sim8 {ECO:0000313|EMBL:AAQ64891.1};
RX   PubMed=12930753;
RA   Schlenke T.A., Begun D.J.;
RT   "Natural selection drives Drosophila immune system evolution.";
RL   Genetics 164:1471-1480(2003).
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DR   EMBL; AY354414; AAQ64891.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6V1V4; -.
DR   EnsemblMetazoa; FBtr0352645; FBpp0317197; FBgn0067503.
DR   Bgee; FBgn0067503; Expressed in embryo and 3 other cell types or tissues.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR46680; NF-KAPPA-B INHIBITOR ALPHA; 1.
DR   PANTHER; PTHR46680:SF3; NF-KAPPA-B INHIBITOR CACTUS; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 2.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          229..251
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          265..297
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          1..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          171..212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..105
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..131
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         360
FT                   /evidence="ECO:0000313|EMBL:AAQ64891.1"
SQ   SEQUENCE   360 AA;  38468 MW;  063A3B4C3AAC095C CRC64;
     MPSPTKAAEA ATKATATSDC SCSAASVEQR APSNAANPSS SLATSGKIGG KTQDQTAAIN
     KQKEFAVPNE TSDSGFISGP QSSQIFSEEI VPDREEQDKD QQESAPQKEQ PVVLDSGIID
     EEEDQEEQEK EEEHQDTTTA TADSMRLKHS ADTGIPQWTV ESHLVSRGEQ LNNLGQSSST
     QITGRSKVQS STASTANANP SGSGATSSAP PSSINIMNAW EQFYQQNDDG DTPLHLACIS
     GSVDVVAALI RMAPHPCLLN IQNDVAQTPL HLAALTAQPN IMRILLLAGA EPTVRDRHGN
     TALHLSCIAG EKQCVRALTE KFGATEIHEA HRQYGHRSND KAVSSLSYAR LPADLEIRNY
//