ID   Q6V6N2_DROSI            Unreviewed;       490 AA.
AC   Q6V6N2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Hmu {ECO:0000313|EMBL:AAQ64709.1};
DE   Flags: Fragment;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240 {ECO:0000313|EMBL:AAQ64709.1};
RN   [1] {ECO:0000313|EMBL:AAQ64709.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Sim6 {ECO:0000313|EMBL:AAQ64709.1};
RX   PubMed=12930753;
RA   Schlenke T.A., Begun D.J.;
RT   "Natural selection drives Drosophila immune system evolution.";
RL   Genetics 164:1471-1480(2003).
CC   -!- SIMILARITY: Belongs to the strictosidine synthase family.
CC       {ECO:0000256|ARBA:ARBA00009191}.
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DR   EMBL; AY349750; AAQ64709.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6V6N2; -.
DR   GO; GO:0016844; F:strictosidine synthase activity; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR018119; Strictosidine_synth_cons-reg.
DR   PANTHER; PTHR10426:SF106; ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED; 1.
DR   PANTHER; PTHR10426; STRICTOSIDINE SYNTHASE-RELATED; 1.
DR   Pfam; PF20067; SSL_N; 1.
DR   Pfam; PF03088; Str_synth; 1.
DR   PRINTS; PR01217; PRICHEXTENSN.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
PE   3: Inferred from homology;
FT   DOMAIN          134..219
FT                   /note="Strictosidine synthase conserved region"
FT                   /evidence="ECO:0000259|Pfam:PF03088"
FT   REGION          388..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..490
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAQ64709.1"
FT   NON_TER         490
FT                   /evidence="ECO:0000313|EMBL:AAQ64709.1"
SQ   SEQUENCE   490 AA;  53160 MW;  9D12749B2C34AD83 CRC64;
     VTPPKDLKGA LESNFHLEGA ERLLEGRVYG PECLIARNNE IYTGIHGGEV IKLTSNHVTH
     VTKIGQPCED IYEESRCGRP LGLAFDTQAN NLIVADAYYG LWQVDLGTNK KTLLVSPAQE
     LAGKSINRPA KIFNGVTVSK QGDVYWTDSS SDFTIEDLVF ASFANPSGRL FKYNRSKNVS
     EVLLDELAFA NGLALSPNED FIVVAETGAM RLTKYHLKGA KAGQSEVFVD GLPGLPDNLT
     PDAEGIWVPL VQSADSEHPN GFTLFTRFPS VRLFLARMLA LFELPFRYLN SVYPNKFSQR
     FVHFVGHMES ITVLAPKRTT VVRVDWNGNI VGSLHGFDKS AATVSHVLEF QDFLFLGSPT
     NQYLARVKSP KAKQPTLKVR NVRVEGEGLE ASIGVPPSTA TPKPKAAPST TTPKPTTTTT
     TPKPTTTTTT TTTTPKPTTT TTTKKPTTTT TTTTTTPKPT TTKPPATKPS TTTTTTTTPK
     PTTTTTTTPA
//