ID Q6ZY41_YERFR Unreviewed; 346 AA.
AC Q6ZY41;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:CAG25885.1};
OS Yersinia frederiksenii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=29484 {ECO:0000313|EMBL:CAG25885.1};
RN [1] {ECO:0000313|EMBL:CAG25885.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y1 {ECO:0000313|EMBL:CAG25885.1};
RX PubMed=15358429; DOI=10.1016/j.femsle.2004.08.005;
RA Demarta A., De Respinis S., Dolina M., Peduzzi R.;
RT "Molecular typing of Yersinia frederiksenii strains by means of 16s rDNA
RT and gyrB genes sequence analyses.";
RL FEMS Microbiol. Lett. 238:423-428(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; AJ639642; CAG25885.1; -; Genomic_DNA.
DR AlphaFoldDB; Q6ZY41; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR InterPro; IPR018522; TopoIIA_CS.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR Pfam; PF01751; Toprim; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR PRINTS; PR00418; TPI2FAMILY.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR PROSITE; PS50880; TOPRIM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:CAG25885.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 308..346
FT /note="Toprim"
FT /evidence="ECO:0000259|PROSITE:PS50880"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAG25885.1"
FT NON_TER 346
FT /evidence="ECO:0000313|EMBL:CAG25885.1"
SQ SEQUENCE 346 AA; 38507 MW; 358318B77DC63D09 CRC64;
VSGGLHGVGV SVVNALSEKL ELVIRREGKV HEQTYRMGVP QAPLKVVGET DQTGTTVRFW
PSFETFTNNT EFQYEILAKR LRELSFLNSG VSIKLRDKRN DREDHFHYEG GIKAFVEYLN
KNKTPIHPKV FYFSTVKDDI GVEVALQWND GFQENIYCFT NNIPQRDGGT HLVGFRTAMT
RTLNSYMDKE GYSKKAKISA TGDDAREGLI AVVSVKVPDP KFSSQTKDKL VSSEVKTAVE
TLMNEKLVEY LLENPTDAKI VVGKIIDAAR AREAARKARE MTRRKGALDL AGLPGKLADC
QERDPALSEL YLVEGDSAGG SAKQGRNRKN QAILPLKGKI LNVEKA
//
