ID Q71SV2_ONCHC Unreviewed; 574 AA.
AC Q71SV2;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
DE Flags: Fragment;
GN Name=ER4 {ECO:0000313|EMBL:AAQ14311.1};
OS Oncidium hybrid cultivar (Orchid).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Asparagales; Orchidaceae;
OC Epidendroideae; Cymbidieae; Oncidiinae; Oncidium.
OX NCBI_TaxID=141207 {ECO:0000313|EMBL:AAQ14311.1};
RN [1] {ECO:0000313|EMBL:AAQ14311.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Petal {ECO:0000313|EMBL:AAQ14311.1};
RA Liu H.-C., Do Y.-Y., Huang P.-L.;
RT "Molecular Cloning and Characterization of cDNAs Encoding Ethylene Receptor
RT Homologs from Oncidium.";
RL Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC Evidence={ECO:0000256|ARBA:ARBA00001935};
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ethylene receptor family.
CC {ECO:0000256|ARBA:ARBA00009842}.
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DR EMBL; AF276236; AAQ14311.1; -; mRNA.
DR AlphaFoldDB; Q71SV2; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051740; F:ethylene binding; IEA:UniProt.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0010105; P:negative regulation of ethylene-activated signaling pathway; IEA:UniProt.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR24423:SF625; ETHYLENE RESPONSE SENSOR 1; 1.
DR PANTHER; PTHR24423; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 2: Evidence at transcript level;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Ethylene signaling pathway {ECO:0000256|ARBA:ARBA00022745};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAQ14311.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 293..529
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 550..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAQ14311.1"
SQ SEQUENCE 574 AA; 63789 MW; DFB644D1E81A82C6 CRC64;
FGAFIVLCGA THLINLWTFT MHSRTLAIVM TVAKVSTAVV SCATALMLVH IIPDLLSVKT
RELFLRNKAE ELDREMGLIR TQEETGRHVR MLTHEIRSTL DRHTILKTTL VELGRTLDLA
ECALWMPLRT GLHLQLSHTL NNKIPGGSGG SINLPIVNQI FNSSRAGRIP NTCPLARFQP
YTGRYVPQEV VAVRVPLLHL SNFQINDWPE LSPKSFAVLV LMLPSDSARK WHAYELELVE
VVADQVAVAL SHAAILEESM RARDLLMDQN VALDLARREA EMAIRARNDF LAVMNHEMRT
PMHAIIALSS LLLETELTPE QRLMVETILK SSNLLATLIN DVLDLSKLED GSFELEATIF
NLHTVFREAV NLIKPIAAVK KLSLFVSLAP DLPSCAIGDE KRLLQIMLNV VGNAVKFTKE
GTIFITANIA KPDSLRDPDF YPAPTDGHFY LRVQVKDTGC GISPQELPHL FTKFAHTQNG
SDKGYSGSGL GLAICKRFVN LMKGHIWLES EGIGKGCTTI FIVKLGMSED PTPRYQQKLL
PPIRAGQAEA DPFGLKPAAP KDELMPKIRY QRSL
//
