ID Q72DA3_DESVH Unreviewed; 419 AA.
AC Q72DA3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Uracil permease {ECO:0000313|EMBL:AAS95506.1};
GN Name=uraA {ECO:0000313|EMBL:AAS95506.1};
GN OrderedLocusNames=DVU_1026 {ECO:0000313|EMBL:AAS95506.1};
OS Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM
OS B-1760 / Hildenborough).
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae; Nitratidesulfovibrio.
OX NCBI_TaxID=882 {ECO:0000313|EMBL:AAS95506.1, ECO:0000313|Proteomes:UP000002194};
RN [1] {ECO:0000313|EMBL:AAS95506.1, ECO:0000313|Proteomes:UP000002194}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough
RC {ECO:0000313|Proteomes:UP000002194};
RX PubMed=15077118; DOI=10.1038/nbt959;
RA Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA Kolonay J.F., Eisen J.A., Ward N., Methe B., Brinkac L.M., Daugherty S.C.,
RA Deboy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C.,
RA Sullivan S.A., Fouts D., Haft D.H., Selengut J., Peterson J.D.,
RA Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M.,
RA Tran K., Khouri H., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D.,
RA Voordouw G., Fraser C.M.;
RT "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT Desulfovibrio vulgaris Hildenborough.";
RL Nat. Biotechnol. 22:554-559(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; AE017285; AAS95506.1; -; Genomic_DNA.
DR RefSeq; WP_010938325.1; NC_002937.3.
DR RefSeq; YP_010247.1; NC_002937.3.
DR AlphaFoldDB; Q72DA3; -.
DR SMR; Q72DA3; -.
DR STRING; 882.DVU_1026; -.
DR PaxDb; 882-DVU_1026; -.
DR EnsemblBacteria; AAS95506; AAS95506; DVU_1026.
DR KEGG; dvu:DVU_1026; -.
DR PATRIC; fig|882.5.peg.964; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_1_2_7; -.
DR OrthoDB; 9779092at2; -.
DR PhylomeDB; Q72DA3; -.
DR Proteomes; UP000002194; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002194};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 419 AA; 43386 MW; 139DBFC269F52D96 CRC64;
MTTDPRFIPE YNFRFRDGLI GAQMLFVAFG ALVLVPLLTG LDPNVALFAA GCATLIFQAI
TRGKVPIFLA SSFAFIAPII YGVQTWGIPG TLCGLTAAGL VYMALSALIR VQGPGVVERV
LPPIVTGPVI MVIGLILSPV AVFMAIGKTG DGAVQLIPKD KAMIVAMVSL ASTVIASLLG
RGFVKLIPIF CGIVAGYATS LFFGIVDFTP VLKAPWFAVP NFVTPEWNLD AILFIVPVAI
APAIEHVGGI LAIGSVTGKN YLEDPGIDRT LFADSIATMV ATSVGGPPCT TYAEVTGAIA
LTRAFNPAIL TWAAITAVCL AFVGKLGALL TTIPSPVMGG IMVLLFGAIT VVGMNSLVRA
GQDLMVPRNM AVVAIILVFG LGGMAFNVGE FSLQGIGLAG ITGVLLNLVL PGRRAASGR
//
