GenomeNet

Database: UniProt
Entry: Q72G59_DESVH
LinkDB: Q72G59_DESVH
Original site: Q72G59_DESVH 
ID   Q72G59_DESVH            Unreviewed;       437 AA.
AC   Q72G59;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   05-JUL-2017, entry version 115.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA-1 {ECO:0000313|EMBL:AAS94485.1};
GN   OrderedLocusNames=DVU_0001 {ECO:0000313|EMBL:AAS94485.1};
OS   Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 /
OS   NCIMB 8303).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Desulfovibrio.
OX   NCBI_TaxID=882 {ECO:0000313|EMBL:AAS94485.1, ECO:0000313|Proteomes:UP000002194};
RN   [1] {ECO:0000313|EMBL:AAS94485.1, ECO:0000313|Proteomes:UP000002194}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303
RC   {ECO:0000313|Proteomes:UP000002194};
RX   PubMed=15077118; DOI=10.1038/nbt959;
RA   Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA   Kolonay J.F., Eisen J.A., Ward N., Methe B., Brinkac L.M.,
RA   Daugherty S.C., Deboy R.T., Dodson R.J., Durkin A.S., Madupu R.,
RA   Nelson W.C., Sullivan S.A., Fouts D., Haft D.H., Selengut J.,
RA   Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D.,
RA   Dimitrov G., Hance M., Tran K., Khouri H., Gill J., Utterback T.R.,
RA   Feldblyum T.V., Wall J.D., Voordouw G., Fraser C.M.;
RT   "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT   Desulfovibrio vulgaris Hildenborough.";
RL   Nat. Biotechnol. 22:554-559(2004).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AE017285; AAS94485.1; -; Genomic_DNA.
DR   RefSeq; WP_010937312.1; NC_002937.3.
DR   RefSeq; YP_009226.1; NC_002937.3.
DR   ProteinModelPortal; Q72G59; -.
DR   STRING; 882.DVU0001; -.
DR   PaxDb; Q72G59; -.
DR   EnsemblBacteria; AAS94485; AAS94485; DVU_0001.
DR   GeneID; 2794438; -.
DR   KEGG; dvu:DVU0001; -.
DR   PATRIC; fig|882.5.peg.1; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; DFRYLQG; -.
DR   OrthoDB; POG091H02FF; -.
DR   PhylomeDB; Q72G59; -.
DR   Proteomes; UP000002194; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002194};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002194}.
FT   DOMAIN      136    264       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      342    411       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   437 AA;  49501 MW;  285436BB6A83E002 CRC64;
     MLQQALRQHL RQTCSEQELH QWFDPLDLRL DDAQQRLEVR FPHPHFARWF EAQALERFTA
     GVRDVVGTSV ALVFPEGIKT TDRSTVQPPS QPPLASESVA CPFGAAFTFD AFITNRKNQF
     PLAAAREAAR NGHQRTYNPF VLCGASGNGK THLLRALANE LAALYGTDAV FCGSAEELHD
     RYNTEERLAM RRTLCAHRAL LLDDLHRLRA LPDLREELTA LFDHFYDHGK QMAFAYAGRL
     SDLDFLEAPL RSRLELGLIV DLKEPDLDVR VRYIHARCAA LSLQLAREHV LTLAQRCHEF
     RHLSGLLLKV AAYRDMVGRD ILDRELEQIL RNTDSGPERA VAPDTIISAA AEHFGVTPRD
     ILSDKRQQHI VQARQVAMFL CRELIGSSFP ALGRMFGGKD HSTAMYAVKK IKKLQYDNKD
     MHALVAELKR RCLNHDG
//
DBGET integrated database retrieval system