ID Q72LN5_THET2 Unreviewed; 545 AA.
AC Q72LN5;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Fumarate/succinate/L-aspartate dehydrogenases {ECO:0000313|EMBL:AAS80371.1};
GN OrderedLocusNames=TT_C0023 {ECO:0000313|EMBL:AAS80371.1};
OS Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=262724 {ECO:0000313|EMBL:AAS80371.1, ECO:0000313|Proteomes:UP000000592};
RN [1] {ECO:0000313|EMBL:AAS80371.1, ECO:0000313|Proteomes:UP000000592}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-163 / DSM 7039 / HB27
RC {ECO:0000313|Proteomes:UP000000592};
RX PubMed=15064768; DOI=10.1038/nbt956;
RA Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H.,
RA Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C.,
RA Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P.,
RA Overbeek R., Kramer W., Merkl R., Gottschalk G., Fritz H.-J.;
RT "The genome sequence of the extreme thermophile Thermus thermophilus.";
RL Nat. Biotechnol. 22:547-553(2004).
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DR EMBL; AE017221; AAS80371.1; -; Genomic_DNA.
DR RefSeq; WP_011172481.1; NZ_CP133179.1.
DR AlphaFoldDB; Q72LN5; -.
DR KEGG; tth:TT_C0023; -.
DR eggNOG; COG3573; Bacteria.
DR HOGENOM; CLU_022946_0_0_0; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000000592; Chromosome.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR014614; KsdD_DH.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PIRSF; PIRSF036654; UCP036654; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 4..526
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 545 AA; 59317 MW; E772B88F3710CF71 CRC64;
MDADLVMVGG GLSGLVVATE VAQRGKRVLL LEQEPYLGGQ AFWSFGGLFL VDSPEQRRLG
VRDSVELAFQ DWMGAAGYDR EEDYWGRRFA EAYLEFAAGE KRAWLASLGV RFFPVVGWAE
RGGGLATGHG NSVPRFHIVW GTGPGLLAPF LRKVEALKAE GTLRVLLRHR VEEVLVEGGK
AVGVAGVVLE EDPKPRGAPT SRKAVGGFRF LAQAVVLATG GIGANLDLVR RHWPARMGRP
PKRMLSGVPD HVDGSGLFLA ERAGARLVNL DRMWHYPEGV ENHTPIWTGH GIRILPGPSP
LWVDATGKRL PPPLFPGFDA LETLRYLRST GFDWSWFILD LATLKKEFAL SGSEQNPDLT
GKSWLGVVRN RLLGPAAPVR AFLERGKDFL VAQDLSELMR KMEALAPGVL DPGRLEREVK
ARDRELLNPF AKDGQVLMVH AFRRYLGDRL FRVAKPHPFL SGKGPLVAVR LWTLTRKTLG
GIQTDLKGRA LRPSGEPLPG LFAAGEAAGF GGGAFHGYKA LEGTFLGGCL FSGLQAAKGV
LDGLE
//
