ID Q72PU0_LEPIC Unreviewed; 342 AA.
AC Q72PU0;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Capsule biosynthesis protein {ECO:0000313|EMBL:AAS70946.1};
GN Name=capA {ECO:0000313|EMBL:AAS70946.1};
GN OrderedLocusNames=LIC_12377 {ECO:0000313|EMBL:AAS70946.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni
OS (strain Fiocruz L1-130).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=267671 {ECO:0000313|EMBL:AAS70946.1, ECO:0000313|Proteomes:UP000007037};
RN [1] {ECO:0000313|EMBL:AAS70946.1, ECO:0000313|Proteomes:UP000007037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fiocruz L1-130 {ECO:0000313|EMBL:AAS70946.1,
RC ECO:0000313|Proteomes:UP000007037};
RX PubMed=15028702; DOI=10.1128/JB.186.7.2164-2172.2004;
RA Nascimento A.L., Ko A.I., Martins E.A., Monteiro-Vitorello C.B., Ho P.L.,
RA Haake D.A., Verjovski-Almeida S., Hartskeerl R.A., Marques M.V.,
RA Oliveira M.C., Menck C.F., Leite L.C., Carrer H., Coutinho L.L.,
RA Degrave W.M., Dellagostin O.A., El-Dorry H., Ferro E.S., Ferro M.I.,
RA Furlan L.R., Gamberini M., Giglioti E.A., Goes-Neto A., Goldman G.H.,
RA Goldman M.H., Harakava R., Jeronimo S.M., Junqueira-De-Azevedo I.L.,
RA Kimura E.T., Kuramae E.E., Lemos E.G., Lemos M.V., Marino C.L., Nunes L.R.,
RA De Oliveira R.C., Pereira G.G., Reis M.S., Schriefer A., Siqueira W.J.,
RA Sommer P., Tsai S.M., Simpson A.J., Ferro J.A., Camargo L.E.,
RA Kitajima J.P., Setubal J.C., Van Sluys M.A.;
RT "Comparative genomics of two Leptospira interrogans serovars reveals novel
RT insights into physiology and pathogenesis.";
RL J. Bacteriol. 186:2164-2172(2004).
CC -!- SIMILARITY: Belongs to the CapA family.
CC {ECO:0000256|ARBA:ARBA00005662}.
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DR EMBL; AE016823; AAS70946.1; -; Genomic_DNA.
DR RefSeq; WP_001250026.1; NC_005823.1.
DR AlphaFoldDB; Q72PU0; -.
DR GeneID; 61142257; -.
DR KEGG; lic:LIC_12377; -.
DR HOGENOM; CLU_038823_1_1_12; -.
DR Proteomes; UP000007037; Chromosome I.
DR CDD; cd07381; MPP_CapA; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR019079; Capsule_synth_CapA.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR PANTHER; PTHR33393:SF11; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR Pfam; PF09587; PGA_cap; 1.
DR SMART; SM00854; PGA_cap; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
FT DOMAIN 25..265
FT /note="Capsule synthesis protein CapA"
FT /evidence="ECO:0000259|SMART:SM00854"
SQ SEQUENCE 342 AA; 37767 MW; AB7719C178DBB566 CRC64;
MRQTFILSVL FLFSFGLLGD SKTIKIKAVG DMVPGTNFPQ PLNIQDPRSF LFGKVESYLK
GADLLFGNFE STLTDYPNTS KDTSRKMIFA FRTPPAYAKV LKEVGFDILS IANNHSLDFH
EQGFVDTQKN LSDVGIRYTG KKGMITYMNV KDISVAWIGF SHLKSHNNVN EIGEGVALVK
EAKKKAQLVF ISFHGGAEGG PALHVKNQME RFYGEYRGNL VEFSHSLIDA GADLVIGHGP
HLVRAMELYK GRLIAYSLGN FMGYRALSSR GIVGYSLVLE VEVDSQGKFV KGKILPLQLD
SASIPEYDPE KKTIDLMKKL TKEDFPGKGP KIADDGTILP GT
//
